Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

NOBINs and other axially chiral entities have received a great deal of interest in recent years. Here, the authors report the kinetic resolution of racemic amino phenols and the enantioselective preparation of axially chiral N-aryl sulfonamides with excellent level of enantiopurity and broad substra...

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Autores principales:	Shenci Lu, Shawn Voon Hwee Ng, Kaitlyn Lovato, Jun-Yang Ong, Si Bei Poh, Xiao Qian Ng, László Kürti, Yu Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2e0c7cd9299b4d6198b4ac8b2e17a7aa
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spelling	oai:doaj.org-article:2e0c7cd9299b4d6198b4ac8b2e17a7aa2021-12-02T17:31:37ZPractical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation10.1038/s41467-019-10940-42041-1723https://doaj.org/article/2e0c7cd9299b4d6198b4ac8b2e17a7aa2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10940-4https://doaj.org/toc/2041-1723NOBINs and other axially chiral entities have received a great deal of interest in recent years. Here, the authors report the kinetic resolution of racemic amino phenols and the enantioselective preparation of axially chiral N-aryl sulfonamides with excellent level of enantiopurity and broad substrate scope.Shenci LuShawn Voon Hwee NgKaitlyn LovatoJun-Yang OngSi Bei PohXiao Qian NgLászló KürtiYu ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shenci Lu Shawn Voon Hwee Ng Kaitlyn Lovato Jun-Yang Ong Si Bei Poh Xiao Qian Ng László Kürti Yu Zhao Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation
description	NOBINs and other axially chiral entities have received a great deal of interest in recent years. Here, the authors report the kinetic resolution of racemic amino phenols and the enantioselective preparation of axially chiral N-aryl sulfonamides with excellent level of enantiopurity and broad substrate scope.
format	article
author	Shenci Lu Shawn Voon Hwee Ng Kaitlyn Lovato Jun-Yang Ong Si Bei Poh Xiao Qian Ng László Kürti Yu Zhao
author_facet	Shenci Lu Shawn Voon Hwee Ng Kaitlyn Lovato Jun-Yang Ong Si Bei Poh Xiao Qian Ng László Kürti Yu Zhao
author_sort	Shenci Lu
title	Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation
title_short	Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation
title_full	Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation
title_fullStr	Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation
title_full_unstemmed	Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation
title_sort	practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective n-alkylation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2e0c7cd9299b4d6198b4ac8b2e17a7aa
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Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

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