The Candida glabrata Upc2A transcription factor is a global regulator of antifungal drug resistance pathways.
The most commonly used antifungal drugs are the azole compounds, which interfere with biosynthesis of the fungal-specific sterol: ergosterol. The pathogenic yeast Candida glabrata commonly acquires resistance to azole drugs like fluconazole via mutations in a gene encoding a transcription factor cal...
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Autores principales: | Bao Gia Vu, Mark A Stamnes, Yu Li, P David Rogers, W Scott Moye-Rowley |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Acceso en línea: | https://doaj.org/article/2e15523381bb4fc399fa53d9a69a1cda |
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