Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes

All biological processes associated with high sports performance, including energy metabolism, are influenced by genetics. DNA sequence variations in such genes, single nucleotide variants (SNVs), could confer genetic advantages that can be exploited to achieve optimal athletic performance. Ignoranc...

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Autores principales:	Olga V. Balberova, Evgeny V. Bykov, German V. Medvedev, Margarita A. Zhogina, Kirill V. Petrov, Marina M. Petrova, Mustafa Al-Zamil, Vera V. Trefilova, Polina S. Goncharova, Natalia A. Shnayder
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	personalized medicine sports genetics candidate genes single nucleotide variant polymorphism energy metabolism Genetics QH426-470
Acceso en línea:	https://doaj.org/article/2e166168e71447d0a794c8e97623184f
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spelling	oai:doaj.org-article:2e166168e71447d0a794c8e97623184f2021-11-25T17:40:44ZCandidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes10.3390/genes121116822073-4425https://doaj.org/article/2e166168e71447d0a794c8e97623184f2021-10-01T00:00:00Zhttps://www.mdpi.com/2073-4425/12/11/1682https://doaj.org/toc/2073-4425All biological processes associated with high sports performance, including energy metabolism, are influenced by genetics. DNA sequence variations in such genes, single nucleotide variants (SNVs), could confer genetic advantages that can be exploited to achieve optimal athletic performance. Ignorance of these features can create genetic “barriers” that prevent professional athletes from pursuing a career in sports. Predictive Genomic DNA Profiling reveals single nucleotide variations (SNV) that may be associated with better suitability for endurance, strength and speed sports. (1) Background: To conduct a research on candidate genes associated with regulation of skeletal muscle energy metabolism among athletes. (2) Methods: We have searched for articles in SCOPUS, Web of Science, Google Scholar, Clinical keys, PubMed, e-LIBRARY databases for the period of 2010–2020 using keywords and keywords combinations; (4) Conclusions: Identification of genetic markers associated with the regulation of energy metabolism in skeletal muscles can help sports physicians and coaches develop personalized strategies for selecting children, teenagers and young adults for endurance, strength and speed sports (such as jogging, middle or long distance runs). However, the multifactorial aspect of sport performances, including impact of genetics, epigenetics, environment (training and etc.), is important for personalized strategies for selecting of athletes. This approach could improve sports performance and reduce the risk of sports injuries to the musculoskeletal system.Olga V. BalberovaEvgeny V. BykovGerman V. MedvedevMargarita A. ZhoginaKirill V. PetrovMarina M. PetrovaMustafa Al-ZamilVera V. TrefilovaPolina S. GoncharovaNatalia A. ShnayderMDPI AGarticlepersonalized medicinesports geneticscandidate genessingle nucleotide variantpolymorphismenergy metabolismGeneticsQH426-470ENGenes, Vol 12, Iss 1682, p 1682 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	personalized medicine sports genetics candidate genes single nucleotide variant polymorphism energy metabolism Genetics QH426-470
spellingShingle	personalized medicine sports genetics candidate genes single nucleotide variant polymorphism energy metabolism Genetics QH426-470 Olga V. Balberova Evgeny V. Bykov German V. Medvedev Margarita A. Zhogina Kirill V. Petrov Marina M. Petrova Mustafa Al-Zamil Vera V. Trefilova Polina S. Goncharova Natalia A. Shnayder Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes
description	All biological processes associated with high sports performance, including energy metabolism, are influenced by genetics. DNA sequence variations in such genes, single nucleotide variants (SNVs), could confer genetic advantages that can be exploited to achieve optimal athletic performance. Ignorance of these features can create genetic “barriers” that prevent professional athletes from pursuing a career in sports. Predictive Genomic DNA Profiling reveals single nucleotide variations (SNV) that may be associated with better suitability for endurance, strength and speed sports. (1) Background: To conduct a research on candidate genes associated with regulation of skeletal muscle energy metabolism among athletes. (2) Methods: We have searched for articles in SCOPUS, Web of Science, Google Scholar, Clinical keys, PubMed, e-LIBRARY databases for the period of 2010–2020 using keywords and keywords combinations; (4) Conclusions: Identification of genetic markers associated with the regulation of energy metabolism in skeletal muscles can help sports physicians and coaches develop personalized strategies for selecting children, teenagers and young adults for endurance, strength and speed sports (such as jogging, middle or long distance runs). However, the multifactorial aspect of sport performances, including impact of genetics, epigenetics, environment (training and etc.), is important for personalized strategies for selecting of athletes. This approach could improve sports performance and reduce the risk of sports injuries to the musculoskeletal system.
format	article
author	Olga V. Balberova Evgeny V. Bykov German V. Medvedev Margarita A. Zhogina Kirill V. Petrov Marina M. Petrova Mustafa Al-Zamil Vera V. Trefilova Polina S. Goncharova Natalia A. Shnayder
author_facet	Olga V. Balberova Evgeny V. Bykov German V. Medvedev Margarita A. Zhogina Kirill V. Petrov Marina M. Petrova Mustafa Al-Zamil Vera V. Trefilova Polina S. Goncharova Natalia A. Shnayder
author_sort	Olga V. Balberova
title	Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes
title_short	Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes
title_full	Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes
title_fullStr	Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes
title_full_unstemmed	Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes
title_sort	candidate genes of regulation of skeletal muscle energy metabolism in athletes
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/2e166168e71447d0a794c8e97623184f
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Candidate Genes of Regulation of Skeletal Muscle Energy Metabolism in Athletes

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