Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis

Bacterial meningitis is one of the critical diseases that needs to be diagnosed and treated promptly. Recent diagnostics of high sensitivity and specificity rates, such as PCR, helped with such presentation, especially in cases with prior antibiotics that led to culture negativity. However, the time...

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Autores principales:	Nourah Alruqaie, Yara Falatah, Fawaz Alzahrani, Musaed Alharbi
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	meningitis Group B Streptococcus (GBS) multiplex PCR CSF infection neonate Pediatrics RJ1-570
Acceso en línea:	https://doaj.org/article/2e206183f0cd4893a97b3b1186ef96c6
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spelling	oai:doaj.org-article:2e206183f0cd4893a97b3b1186ef96c62021-12-01T00:29:19ZCase Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis2296-236010.3389/fped.2021.752235https://doaj.org/article/2e206183f0cd4893a97b3b1186ef96c62021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fped.2021.752235/fullhttps://doaj.org/toc/2296-2360Bacterial meningitis is one of the critical diseases that needs to be diagnosed and treated promptly. Recent diagnostics of high sensitivity and specificity rates, such as PCR, helped with such presentation, especially in cases with prior antibiotics that led to culture negativity. However, the time window of PCR positivity is not well-studied, with scattered reports of different periods of positivity. Here, we report a case of neonatal GBS meningitis with positive PCR for more than 80 days from starting antibiotics.Nourah AlruqaieNourah AlruqaieYara FalatahFawaz AlzahraniFawaz AlzahraniMusaed AlharbiMusaed AlharbiMusaed AlharbiFrontiers Media S.A.articlemeningitisGroup B Streptococcus (GBS)multiplex PCRCSF infectionneonatePediatricsRJ1-570ENFrontiers in Pediatrics, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	meningitis Group B Streptococcus (GBS) multiplex PCR CSF infection neonate Pediatrics RJ1-570
spellingShingle	meningitis Group B Streptococcus (GBS) multiplex PCR CSF infection neonate Pediatrics RJ1-570 Nourah Alruqaie Nourah Alruqaie Yara Falatah Fawaz Alzahrani Fawaz Alzahrani Musaed Alharbi Musaed Alharbi Musaed Alharbi Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis
description	Bacterial meningitis is one of the critical diseases that needs to be diagnosed and treated promptly. Recent diagnostics of high sensitivity and specificity rates, such as PCR, helped with such presentation, especially in cases with prior antibiotics that led to culture negativity. However, the time window of PCR positivity is not well-studied, with scattered reports of different periods of positivity. Here, we report a case of neonatal GBS meningitis with positive PCR for more than 80 days from starting antibiotics.
format	article
author	Nourah Alruqaie Nourah Alruqaie Yara Falatah Fawaz Alzahrani Fawaz Alzahrani Musaed Alharbi Musaed Alharbi Musaed Alharbi
author_facet	Nourah Alruqaie Nourah Alruqaie Yara Falatah Fawaz Alzahrani Fawaz Alzahrani Musaed Alharbi Musaed Alharbi Musaed Alharbi
author_sort	Nourah Alruqaie
title	Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis
title_short	Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis
title_full	Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis
title_fullStr	Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis
title_full_unstemmed	Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis
title_sort	case report: prolonged csf pcr positivity in a neonate with gbs meningitis
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/2e206183f0cd4893a97b3b1186ef96c6
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Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis

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