CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment

Adipose stromal cells (ASC) have been shown to migrate to tumours and promote tumour growth. Using animal models and human tissue samples, the authors show here that ASC recruitment to prostate cancers is mediated by the chemokine CXCL1, which is secreted from tumour cells, and acts on CXCR1 on ASCs...

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Autores principales:	Tao Zhang, Chieh Tseng, Yan Zhang, Olga Sirin, Paul G. Corn, Elsa M. Li-Ning-Tapia, Patricia Troncoso, John Davis, Curtis Pettaway, John Ward, Marsha L. Frazier, Christopher Logothetis, Mikhail G. Kolonin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2e28e089451a4a738fb81e93c004e7a6
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spelling	oai:doaj.org-article:2e28e089451a4a738fb81e93c004e7a62021-12-02T14:38:55ZCXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment10.1038/ncomms116742041-1723https://doaj.org/article/2e28e089451a4a738fb81e93c004e7a62016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11674https://doaj.org/toc/2041-1723Adipose stromal cells (ASC) have been shown to migrate to tumours and promote tumour growth. Using animal models and human tissue samples, the authors show here that ASC recruitment to prostate cancers is mediated by the chemokine CXCL1, which is secreted from tumour cells, and acts on CXCR1 on ASCs.Tao ZhangChieh TsengYan ZhangOlga SirinPaul G. CornElsa M. Li-Ning-TapiaPatricia TroncosoJohn DavisCurtis PettawayJohn WardMarsha L. FrazierChristopher LogothetisMikhail G. KoloninNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tao Zhang Chieh Tseng Yan Zhang Olga Sirin Paul G. Corn Elsa M. Li-Ning-Tapia Patricia Troncoso John Davis Curtis Pettaway John Ward Marsha L. Frazier Christopher Logothetis Mikhail G. Kolonin CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
description	Adipose stromal cells (ASC) have been shown to migrate to tumours and promote tumour growth. Using animal models and human tissue samples, the authors show here that ASC recruitment to prostate cancers is mediated by the chemokine CXCL1, which is secreted from tumour cells, and acts on CXCR1 on ASCs.
format	article
author	Tao Zhang Chieh Tseng Yan Zhang Olga Sirin Paul G. Corn Elsa M. Li-Ning-Tapia Patricia Troncoso John Davis Curtis Pettaway John Ward Marsha L. Frazier Christopher Logothetis Mikhail G. Kolonin
author_facet	Tao Zhang Chieh Tseng Yan Zhang Olga Sirin Paul G. Corn Elsa M. Li-Ning-Tapia Patricia Troncoso John Davis Curtis Pettaway John Ward Marsha L. Frazier Christopher Logothetis Mikhail G. Kolonin
author_sort	Tao Zhang
title	CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
title_short	CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
title_full	CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
title_fullStr	CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
title_full_unstemmed	CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
title_sort	cxcl1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2e28e089451a4a738fb81e93c004e7a6
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CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment

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