CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment

CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment

Adipose stromal cells (ASC) have been shown to migrate to tumours and promote tumour growth. Using animal models and human tissue samples, the authors show here that ASC recruitment to prostate cancers is mediated by the chemokine CXCL1, which is secreted from tumour cells, and acts on CXCR1 on ASCs...

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Autores principales: Tao Zhang, Chieh Tseng, Yan Zhang, Olga Sirin, Paul G. Corn, Elsa M. Li-Ning-Tapia, Patricia Troncoso, John Davis, Curtis Pettaway, John Ward, Marsha L. Frazier, Christopher Logothetis, Mikhail G. Kolonin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
Q
Acceso en línea:https://doaj.org/article/2e28e089451a4a738fb81e93c004e7a6
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