Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis
ABSTRACT The rapid spread of multidrug-resistant strains has created a pressing need for new drug regimens to treat tuberculosis (TB), which kills 1.8 million people each year. Identifying new regimens has been challenging due to the slow growth of the pathogen Mycobacterium tuberculosis (MTB), coup...
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Autores principales: | Shuyi Ma, Suraj Jaipalli, Jonah Larkins-Ford, Jenny Lohmiller, Bree B. Aldridge, David R. Sherman, Sriram Chandrasekaran |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/2e46663689eb483f82794186d5d7f4bf |
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