The Stringent Response Inhibits DNA Replication Initiation in <named-content content-type="genus-species">E. coli</named-content> by Modulating Supercoiling of <italic toggle="yes">oriC</italic>

The Stringent Response Inhibits DNA Replication Initiation in <named-content content-type="genus-species">E. coli</named-content> by Modulating Supercoiling of <italic toggle="yes">oriC</italic>

ABSTRACT The stringent response enables bacteria to respond to a variety of environmental stresses, especially various forms of nutrient limitation. During the stringent response, the cell produces large quantities of the nucleotide alarmone ppGpp, which modulates many aspects of cell physiology, in...

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Autores principales: James A. Kraemer, Allen G. Sanderlin, Michael T. Laub
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
DNA topology
DnaA
ppGpp
replication initiation
stringent response
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/2e4890f49a714dfa9faa376a7b10132c
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