Baseline gene expression signatures in monocytes from multiple sclerosis patients treated with interferon-beta.

Baseline gene expression signatures in monocytes from multiple sclerosis patients treated with interferon-beta.

<h4>Background</h4>A relatively large proportion of relapsing-remitting multiple sclerosis (RRMS) patients do not respond to interferon-beta (IFNb) treatment. In previous studies with peripheral blood mononuclear cells (PBMC), we identified a subgroup of IFNb non-responders that was char...

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Autores principales: Marta F Bustamante, Ramil N Nurtdinov, Jordi Río, Xavier Montalban, Manuel Comabella
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/2e4f0faa57a649f18031ca8a922b4fa5
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