Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

Abstract The outbreak of SARS-CoV-2 (2019-nCoV) virus has highlighted the need for fast and efficacious vaccine development. Stimulation of a proper immune response that leads to protection is highly dependent on presentation of epitopes to circulating T-cells via the HLA complex. SARS-CoV-2 is a la...

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Autores principales: Marek Prachar, Sune Justesen, Daniel Bisgaard Steen-Jensen, Stephan Thorgrimsen, Erik Jurgons, Ole Winther, Frederik Otzen Bagger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2e4f85ebafd44c1a9adb239a6bb78181
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