Microbiological study of dacryocystitis in northwest of Iran

Fatemeh Eslami,1 Hamid Reza Ghasemi Basir,2 Abbas Moradi,3 Shokoufe Heidari Farah3 1Department of Ophthalmology, 2Department of Pathology, 3School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Background: The prevalence of bacterial pathogens isolated from patients with acute...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Eslami F, Ghasemi Basir HR, Moradi A, Heidari Farah S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Dacryocystitis Microbiology Antibiotic susceptibility test Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/2e50aaa6638340e48fec931fab7b273a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2e50aaa6638340e48fec931fab7b273a
record_format	dspace
spelling	oai:doaj.org-article:2e50aaa6638340e48fec931fab7b273a2021-12-02T07:37:59ZMicrobiological study of dacryocystitis in northwest of Iran1177-5483https://doaj.org/article/2e50aaa6638340e48fec931fab7b273a2018-09-01T00:00:00Zhttps://www.dovepress.com/microbiological-study-of-dacryocystitis-in-northwest-of-iran-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Fatemeh Eslami,1 Hamid Reza Ghasemi Basir,2 Abbas Moradi,3 Shokoufe Heidari Farah3 1Department of Ophthalmology, 2Department of Pathology, 3School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Background: The prevalence of bacterial pathogens isolated from patients with acute and chronic dacryocystitis and the pattern of antibiotic susceptibility tests are varied in each region. Moreover, the management of dacryocystitis is only based on clinical observations without microbiological evaluation. The present study aimed to identify epidemiologic and etiologic factors of dacryocystitis in our geographical area.Materials and methods: This cross-sectional and analytical study was carried out in the ophthalmology department of Hamadan University of Medical Sciences (northwest of Iran) during 2016–2017. Nasolacrimal duct discharges were inoculated to culture media including blood agar, eosin methylene blue, chocolate agar, and Sabouraud agar for the determination of microbial agents. Disc diffusion method with MAST antibiogram discs was used for antibiotic susceptibility tests, according to the Clinical and Laboratory Standards Institute, 2017.Results: Of the total 129 patients enrolled in the study, 34.1% had acute dacryocystitis and 65.9% showed chronic type. The result of culture was positive in 75.2% of patients. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Pseudomonas spp., and Candida albicans were the most prevalent microorganisms. The most sensitive antibiotics used against prevalent bacteria were ciprofloxacin (75.9%), ceftriaxone (73.6%), vancomycin (67.8%), and chloramphenicol (60.9%), respectively.Conclusion: The present study is useful for determining the appropriate antibiotic for systemic treatment of dacryocystitis in our region. Ciprofloxacin and vancomycin are the most sensitive antibiotics against the most common isolated microorganisms in both age groups (under and above 10 years) that can be used for empirical therapy of dacryocystitis in both acute and chronic type. Keywords: dacryocystitis, microbiology, antibiotic susceptibility testsEslami FGhasemi Basir HRMoradi AHeidari Farah SDove Medical PressarticleDacryocystitisMicrobiologyAntibiotic susceptibility testOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 1859-1864 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Dacryocystitis Microbiology Antibiotic susceptibility test Ophthalmology RE1-994
spellingShingle	Dacryocystitis Microbiology Antibiotic susceptibility test Ophthalmology RE1-994 Eslami F Ghasemi Basir HR Moradi A Heidari Farah S Microbiological study of dacryocystitis in northwest of Iran
description	Fatemeh Eslami,1 Hamid Reza Ghasemi Basir,2 Abbas Moradi,3 Shokoufe Heidari Farah3 1Department of Ophthalmology, 2Department of Pathology, 3School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Background: The prevalence of bacterial pathogens isolated from patients with acute and chronic dacryocystitis and the pattern of antibiotic susceptibility tests are varied in each region. Moreover, the management of dacryocystitis is only based on clinical observations without microbiological evaluation. The present study aimed to identify epidemiologic and etiologic factors of dacryocystitis in our geographical area.Materials and methods: This cross-sectional and analytical study was carried out in the ophthalmology department of Hamadan University of Medical Sciences (northwest of Iran) during 2016–2017. Nasolacrimal duct discharges were inoculated to culture media including blood agar, eosin methylene blue, chocolate agar, and Sabouraud agar for the determination of microbial agents. Disc diffusion method with MAST antibiogram discs was used for antibiotic susceptibility tests, according to the Clinical and Laboratory Standards Institute, 2017.Results: Of the total 129 patients enrolled in the study, 34.1% had acute dacryocystitis and 65.9% showed chronic type. The result of culture was positive in 75.2% of patients. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Pseudomonas spp., and Candida albicans were the most prevalent microorganisms. The most sensitive antibiotics used against prevalent bacteria were ciprofloxacin (75.9%), ceftriaxone (73.6%), vancomycin (67.8%), and chloramphenicol (60.9%), respectively.Conclusion: The present study is useful for determining the appropriate antibiotic for systemic treatment of dacryocystitis in our region. Ciprofloxacin and vancomycin are the most sensitive antibiotics against the most common isolated microorganisms in both age groups (under and above 10 years) that can be used for empirical therapy of dacryocystitis in both acute and chronic type. Keywords: dacryocystitis, microbiology, antibiotic susceptibility tests
format	article
author	Eslami F Ghasemi Basir HR Moradi A Heidari Farah S
author_facet	Eslami F Ghasemi Basir HR Moradi A Heidari Farah S
author_sort	Eslami F
title	Microbiological study of dacryocystitis in northwest of Iran
title_short	Microbiological study of dacryocystitis in northwest of Iran
title_full	Microbiological study of dacryocystitis in northwest of Iran
title_fullStr	Microbiological study of dacryocystitis in northwest of Iran
title_full_unstemmed	Microbiological study of dacryocystitis in northwest of Iran
title_sort	microbiological study of dacryocystitis in northwest of iran
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/2e50aaa6638340e48fec931fab7b273a
work_keys_str_mv	AT eslamif microbiologicalstudyofdacryocystitisinnorthwestofiran AT ghasemibasirhr microbiologicalstudyofdacryocystitisinnorthwestofiran AT moradia microbiologicalstudyofdacryocystitisinnorthwestofiran AT heidarifarahs microbiologicalstudyofdacryocystitisinnorthwestofiran
_version_	1718399272320237568

Microbiological study of dacryocystitis in northwest of Iran

Ejemplares similares