Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.

<h4>Background</h4>The association between breast cancer and tobacco smoke is currently unclear. The aim of this study was to assess the effect of smoking behaviours on the risk of breast cancer among three ethnic groups of New Zealand women.<h4>Methods</h4>A population-based...

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Autores principales:	Fiona McKenzie, Lis Ellison-Loschmann, Mona Jeffreys, Ridvan Firestone, Neil Pearce, Isabelle Romieu
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2e6124fb3b634fb3919485c1bf0804f5
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spelling	oai:doaj.org-article:2e6124fb3b634fb3919485c1bf0804f52021-11-18T07:47:19ZCigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.1932-620310.1371/journal.pone.0063132https://doaj.org/article/2e6124fb3b634fb3919485c1bf0804f52013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23646186/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>The association between breast cancer and tobacco smoke is currently unclear. The aim of this study was to assess the effect of smoking behaviours on the risk of breast cancer among three ethnic groups of New Zealand women.<h4>Methods</h4>A population-based case-control study was conducted including breast cancer cases registered on the New Zealand Cancer Registry between 2005 and 2007. Controls were matched by ethnicity and 5-year age-group. Logistic regression was used to estimate the association between breast cancer and smoking at different time points across the lifecourse, for each ethnic group. Estimated odds ratios (OR) were adjusted for established risk factors.<h4>Results</h4>The study comprised 1,799 cases (302 Māori, 70 Pacific, 1,427 non-Māori/non-Pacific) and 2,540 controls (746 Māori, 191 Pacific, 1,603 non-Māori/non-Pacific). There was no clear association between smoking and breast cancer for non-Māori/non-Pacific women, although non-Māori/non-Pacific ex-smokers had statistically significant increased risk of breast cancer when smoking duration was 20 years or more, and this remained significant in the fully adjusted model (OR 1.31, 95% CI 1.03 to 1.66). Māori showed more consistent increased risk of breast cancer with increasing duration among current smokers (<20 years OR 1.61, 95% CI 0.55 to 4.74; 20+ years OR 2.03, 95% CI 1.29 to 3.22). There was a clear pattern of shorter duration since smoking cessation being associated with increased likelihood of breast cancer, and this was apparent for all ethnic groups.<h4>Conclusion</h4>There was no clear pattern for cigarette smoking and breast cancer incidence in non-Māori/non-Pacific women, but increased risks were observed for Māori and Pacific women. These findings suggest that lowering the prevalence of smoking, especially among Māori and Pacific women, could be important for reducing breast cancer incidence.Fiona McKenzieLis Ellison-LoschmannMona JeffreysRidvan FirestoneNeil PearceIsabelle RomieuPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 4, p e63132 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Fiona McKenzie Lis Ellison-Loschmann Mona Jeffreys Ridvan Firestone Neil Pearce Isabelle Romieu Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.
description	<h4>Background</h4>The association between breast cancer and tobacco smoke is currently unclear. The aim of this study was to assess the effect of smoking behaviours on the risk of breast cancer among three ethnic groups of New Zealand women.<h4>Methods</h4>A population-based case-control study was conducted including breast cancer cases registered on the New Zealand Cancer Registry between 2005 and 2007. Controls were matched by ethnicity and 5-year age-group. Logistic regression was used to estimate the association between breast cancer and smoking at different time points across the lifecourse, for each ethnic group. Estimated odds ratios (OR) were adjusted for established risk factors.<h4>Results</h4>The study comprised 1,799 cases (302 Māori, 70 Pacific, 1,427 non-Māori/non-Pacific) and 2,540 controls (746 Māori, 191 Pacific, 1,603 non-Māori/non-Pacific). There was no clear association between smoking and breast cancer for non-Māori/non-Pacific women, although non-Māori/non-Pacific ex-smokers had statistically significant increased risk of breast cancer when smoking duration was 20 years or more, and this remained significant in the fully adjusted model (OR 1.31, 95% CI 1.03 to 1.66). Māori showed more consistent increased risk of breast cancer with increasing duration among current smokers (<20 years OR 1.61, 95% CI 0.55 to 4.74; 20+ years OR 2.03, 95% CI 1.29 to 3.22). There was a clear pattern of shorter duration since smoking cessation being associated with increased likelihood of breast cancer, and this was apparent for all ethnic groups.<h4>Conclusion</h4>There was no clear pattern for cigarette smoking and breast cancer incidence in non-Māori/non-Pacific women, but increased risks were observed for Māori and Pacific women. These findings suggest that lowering the prevalence of smoking, especially among Māori and Pacific women, could be important for reducing breast cancer incidence.
format	article
author	Fiona McKenzie Lis Ellison-Loschmann Mona Jeffreys Ridvan Firestone Neil Pearce Isabelle Romieu
author_facet	Fiona McKenzie Lis Ellison-Loschmann Mona Jeffreys Ridvan Firestone Neil Pearce Isabelle Romieu
author_sort	Fiona McKenzie
title	Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.
title_short	Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.
title_full	Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.
title_fullStr	Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.
title_full_unstemmed	Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.
title_sort	cigarette smoking and risk of breast cancer in a new zealand multi-ethnic case-control study.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/2e6124fb3b634fb3919485c1bf0804f5
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Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study.

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