Controlled Measurement Setup for Ultra-Wideband Dielectric Modeling of Muscle Tissue in 20–45 °C Temperature Range
In order to design electromagnetic applicators for diagnostic and therapeutic applications, an adequate dielectric tissue model is required. In addition, tissue temperature will heavily influence the dielectric properties and the dielectric model should, thus, be extended to incorporate this tempera...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/2e61a9fca3f049789048c6ffc9a1c8b6 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:2e61a9fca3f049789048c6ffc9a1c8b6 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:2e61a9fca3f049789048c6ffc9a1c8b62021-11-25T18:58:08ZControlled Measurement Setup for Ultra-Wideband Dielectric Modeling of Muscle Tissue in 20–45 °C Temperature Range10.3390/s212276441424-8220https://doaj.org/article/2e61a9fca3f049789048c6ffc9a1c8b62021-11-01T00:00:00Zhttps://www.mdpi.com/1424-8220/21/22/7644https://doaj.org/toc/1424-8220In order to design electromagnetic applicators for diagnostic and therapeutic applications, an adequate dielectric tissue model is required. In addition, tissue temperature will heavily influence the dielectric properties and the dielectric model should, thus, be extended to incorporate this temperature dependence. Thus, this work has a dual purpose. Given the influence of temperature, dehydration, and probe-to-tissue contact pressure on dielectric measurements, this work will initially present the first setup to actively control and monitor the temperature of the sample, the dehydration rate of the investigated sample, and the applied probe-to-tissue contact pressure. Secondly, this work measured the dielectric properties of porcine muscle in the 0.5–40 GHz frequency range for temperatures from 20 °C to 45 °C. Following measurements, a single-pole Cole–Cole model is presented, in which the five Cole–Cole parameters (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>ϵ</mi><mo>∞</mo></msub></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>σ</mi><mi>s</mi></msub></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>Δ</mo><mi>ϵ</mi></mrow></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>τ</mi></semantics></math></inline-formula>, and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>α</mi></semantics></math></inline-formula>) are given by a first order polynomial as function of tissue temperature. The dielectric model closely agrees with the limited dielectric models known in literature for muscle tissue at 37 °C, which makes it suited for the design of in vivo applicators. Furthermore, the dielectric data at 41–45 °C is of great importance for the design of hyperthermia applicators.Gertjan MaenhoutTomislav MarkovicBart NauwelaersMDPI AGarticlebiological tissuesdielectric measurementdielectric modelmeasurement metadatamuscle tissueopen-ended coaxial probeChemical technologyTP1-1185ENSensors, Vol 21, Iss 7644, p 7644 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
biological tissues dielectric measurement dielectric model measurement metadata muscle tissue open-ended coaxial probe Chemical technology TP1-1185 |
| spellingShingle |
biological tissues dielectric measurement dielectric model measurement metadata muscle tissue open-ended coaxial probe Chemical technology TP1-1185 Gertjan Maenhout Tomislav Markovic Bart Nauwelaers Controlled Measurement Setup for Ultra-Wideband Dielectric Modeling of Muscle Tissue in 20–45 °C Temperature Range |
| description |
In order to design electromagnetic applicators for diagnostic and therapeutic applications, an adequate dielectric tissue model is required. In addition, tissue temperature will heavily influence the dielectric properties and the dielectric model should, thus, be extended to incorporate this temperature dependence. Thus, this work has a dual purpose. Given the influence of temperature, dehydration, and probe-to-tissue contact pressure on dielectric measurements, this work will initially present the first setup to actively control and monitor the temperature of the sample, the dehydration rate of the investigated sample, and the applied probe-to-tissue contact pressure. Secondly, this work measured the dielectric properties of porcine muscle in the 0.5–40 GHz frequency range for temperatures from 20 °C to 45 °C. Following measurements, a single-pole Cole–Cole model is presented, in which the five Cole–Cole parameters (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>ϵ</mi><mo>∞</mo></msub></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>σ</mi><mi>s</mi></msub></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>Δ</mo><mi>ϵ</mi></mrow></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>τ</mi></semantics></math></inline-formula>, and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>α</mi></semantics></math></inline-formula>) are given by a first order polynomial as function of tissue temperature. The dielectric model closely agrees with the limited dielectric models known in literature for muscle tissue at 37 °C, which makes it suited for the design of in vivo applicators. Furthermore, the dielectric data at 41–45 °C is of great importance for the design of hyperthermia applicators. |
| format |
article |
| author |
Gertjan Maenhout Tomislav Markovic Bart Nauwelaers |
| author_facet |
Gertjan Maenhout Tomislav Markovic Bart Nauwelaers |
| author_sort |
Gertjan Maenhout |
| title |
Controlled Measurement Setup for Ultra-Wideband Dielectric Modeling of Muscle Tissue in 20–45 °C Temperature Range |
| title_short |
Controlled Measurement Setup for Ultra-Wideband Dielectric Modeling of Muscle Tissue in 20–45 °C Temperature Range |
| title_full |
Controlled Measurement Setup for Ultra-Wideband Dielectric Modeling of Muscle Tissue in 20–45 °C Temperature Range |
| title_fullStr |
Controlled Measurement Setup for Ultra-Wideband Dielectric Modeling of Muscle Tissue in 20–45 °C Temperature Range |
| title_full_unstemmed |
Controlled Measurement Setup for Ultra-Wideband Dielectric Modeling of Muscle Tissue in 20–45 °C Temperature Range |
| title_sort |
controlled measurement setup for ultra-wideband dielectric modeling of muscle tissue in 20–45 °c temperature range |
| publisher |
MDPI AG |
| publishDate |
2021 |
| url |
https://doaj.org/article/2e61a9fca3f049789048c6ffc9a1c8b6 |
| work_keys_str_mv |
AT gertjanmaenhout controlledmeasurementsetupforultrawidebanddielectricmodelingofmuscletissuein2045ctemperaturerange AT tomislavmarkovic controlledmeasurementsetupforultrawidebanddielectricmodelingofmuscletissuein2045ctemperaturerange AT bartnauwelaers controlledmeasurementsetupforultrawidebanddielectricmodelingofmuscletissuein2045ctemperaturerange |
| _version_ |
1718410454326312960 |