<i>aflN</i> Is Involved in the Biosynthesis of Aflatoxin and Conidiation in <i>Aspergillus flavus</i>
<i>Aspergillus flavus</i> poses a threat to society economy and public health due to aflatoxin production. <i>aflN</i> is a gene located in the aflatoxin gene cluster, but the function of AflN is undefined in <i>Aspergillus flavus</i>. In this study, <i>aflN...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/2e636639075a49c3a9b75b5ed60d5300 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | <i>Aspergillus flavus</i> poses a threat to society economy and public health due to aflatoxin production. <i>aflN</i> is a gene located in the aflatoxin gene cluster, but the function of AflN is undefined in <i>Aspergillus flavus</i>. In this study, <i>aflN</i> is knocked out and overexpressed to study the function of AflN. The results indicated that the loss of AflN leads to the defect of aflatoxin biosynthesis. AflN is also found to play a role in conidiation but not hyphal growth and sclerotia development. Moreover, AlfN is related to the response to environmental oxidative stress and intracellular levels of reactive oxygen species. At last, AflN is involved in the pathogenicity of <i>Aspergillus flavus</i> to host. These results suggested that AflN played important roles in aflatoxin biosynthesis, conidiation and reactive oxygen species generation in <i>Aspergillus flavus</i>, which will be helpful for the understanding of <i>aflN</i> function, and will be beneficial to the prevention and control of <i>Aspergillus flavus</i> and aflatoxins contamination. |
|---|