Chiral phosphoric acid-catalyzed stereodivergent synthesis of trisubstituted allenes and computational mechanistic studies
Despite of the high demand of chiral allenes, their asymmetric synthesis remains a challenge for organic chemists. Here, the authors report a stereodivergent synthesis of trisubstituted allenes via asymmetric additions of oxazolones to activated 1,3-enynes enabled by modification of chiral phosphori...
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Autores principales: | Jiawen Wang, Sujuan Zheng, Subramani Rajkumar, Jinglei Xie, Na Yu, Qian Peng, Xiaoyu Yang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/2e667e3425704a8188b626a984d0d05f |
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