A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors

A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors

Abstract C-X-C chemokine receptor 4 (CXCR4) is over-expressed in multiple human cancers and correlates with tumor aggressiveness, poor prognosis and increased risk for distant metastases. Imaging agents for CXCR4 are thus highly desirable. We developed a novel CXCR4-targeted near-infrared (NIR) fluo...

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Autores principales: Sara Santagata, Luigi Portella, Maria Napolitano, Adelaide Greco, Crescenzo D’Alterio, Maria Vittoria Barone, Antonio Luciano, Matteo Gramanzini, Luigi Auletta, Claudio Arra, Antonella Zannetti, Stefania Scala
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2e67fe00267c494d87da49165cfcd85e
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