Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review

BackgroundCerebellar liponeurocytoma is a rare benign neoplasm of the central nervous system, which arises mainly in adult patients with only 3 cases reported in children. Due to its rarity, the diagnosis and treatment strategies for cerebellar liponeurocytoma remain unclear. The purpose of this stu...

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Autores principales:	Changhui Dong, Yining Jiang, Liyan Zhao, Yubo Wang, Yang Bai, Ying Sun, Yunqian Li
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	case report cerebellar liponeurocytoma children diagnosis liponeurocytoma treatment Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/2e77cbaaa503412aaf9df7007208b121
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spelling	oai:doaj.org-article:2e77cbaaa503412aaf9df7007208b1212021-11-30T23:05:52ZCerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review2234-943X10.3389/fonc.2021.759581https://doaj.org/article/2e77cbaaa503412aaf9df7007208b1212021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.759581/fullhttps://doaj.org/toc/2234-943XBackgroundCerebellar liponeurocytoma is a rare benign neoplasm of the central nervous system, which arises mainly in adult patients with only 3 cases reported in children. Due to its rarity, the diagnosis and treatment strategies for cerebellar liponeurocytoma remain unclear. The purpose of this study was to explore the epidemiology, clinical features, imaging findings, pathological characteristics, different diagnoses, treatment, and prognosis of cerebellar liponeurocytoma in juveniles.Case DescriptionA 5-year-old boy was admitted to the department of neurosurgery due to a 5-month history of headaches, nausea, vomiting, dizziness, dysphoria, as well as visual blurring associated with the peak of the headache. Magnetic resonance imaging showed a 4.9×5.4×6.2 cm mass located in the fourth ventricle and cerebellar vermis combined with hydrocephalus and periventricular edema. The mass was completely removed, and pathological examination indicated a cerebellar liponeurocytoma of the World Health Organization Grade II classification.ConclusionThe present study was the first to report a cerebellar liponeurocytoma with total tumor resection and adjuvant radiotherapy in a pediatric patient. Total tumor resection and postoperative radiotherapy together with close and long-term follow-up seem to be the optimal treatment strategy for juvenile patients. However, the side-effect of radiation needs to be considered.Changhui DongYining JiangLiyan ZhaoYubo WangYang BaiYing SunYunqian LiFrontiers Media S.A.articlecase reportcerebellar liponeurocytomachildrendiagnosisliponeurocytomatreatmentNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	case report cerebellar liponeurocytoma children diagnosis liponeurocytoma treatment Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	case report cerebellar liponeurocytoma children diagnosis liponeurocytoma treatment Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Changhui Dong Yining Jiang Liyan Zhao Yubo Wang Yang Bai Ying Sun Yunqian Li Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review
description	BackgroundCerebellar liponeurocytoma is a rare benign neoplasm of the central nervous system, which arises mainly in adult patients with only 3 cases reported in children. Due to its rarity, the diagnosis and treatment strategies for cerebellar liponeurocytoma remain unclear. The purpose of this study was to explore the epidemiology, clinical features, imaging findings, pathological characteristics, different diagnoses, treatment, and prognosis of cerebellar liponeurocytoma in juveniles.Case DescriptionA 5-year-old boy was admitted to the department of neurosurgery due to a 5-month history of headaches, nausea, vomiting, dizziness, dysphoria, as well as visual blurring associated with the peak of the headache. Magnetic resonance imaging showed a 4.9×5.4×6.2 cm mass located in the fourth ventricle and cerebellar vermis combined with hydrocephalus and periventricular edema. The mass was completely removed, and pathological examination indicated a cerebellar liponeurocytoma of the World Health Organization Grade II classification.ConclusionThe present study was the first to report a cerebellar liponeurocytoma with total tumor resection and adjuvant radiotherapy in a pediatric patient. Total tumor resection and postoperative radiotherapy together with close and long-term follow-up seem to be the optimal treatment strategy for juvenile patients. However, the side-effect of radiation needs to be considered.
format	article
author	Changhui Dong Yining Jiang Liyan Zhao Yubo Wang Yang Bai Ying Sun Yunqian Li
author_facet	Changhui Dong Yining Jiang Liyan Zhao Yubo Wang Yang Bai Ying Sun Yunqian Li
author_sort	Changhui Dong
title	Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review
title_short	Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review
title_full	Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review
title_fullStr	Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review
title_full_unstemmed	Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review
title_sort	cerebellar liponeurocytoma mimicking medulloblastoma: case report of a childhood and literature review
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/2e77cbaaa503412aaf9df7007208b121
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Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review

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