Using the fast fourier transform to accelerate the computational search for RNA conformational switches.

Using complex roots of unity and the Fast Fourier Transform, we design a new thermodynamics-based algorithm, FFTbor, that computes the Boltzmann probability that secondary structures differ by [Formula: see text] base pairs from an arbitrary initial structure of a given RNA sequence. The algorithm,...

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Autores principales: Evan Senter, Saad Sheikh, Ivan Dotu, Yann Ponty, Peter Clote
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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R
Q
Acceso en línea:https://doaj.org/article/2e7cf30e770a41ba88b630c8ce791991
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