RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1.
The human cytidine deaminase APOBEC3G (A3G) is a potent inhibitor of retroviruses and transposable elements and is able to deaminate cytidines to uridines in single-stranded DNA replication intermediates. A3G contains two canonical cytidine deaminase domains (CDAs), of which only the C-terminal one...
Guardado en:
Autores principales: | Hendrik Huthoff, Flavia Autore, Sarah Gallois-Montbrun, Franca Fraternali, Michael H Malim |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2e8cc2ed05354ef5a01c755cd8568ceb |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G
por: Michael Morse, et al.
Publicado: (2017) -
HIV restriction by APOBEC3 in humanized mice.
por: John F Krisko, et al.
Publicado: (2013) -
Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo.
por: Spyridon Stavrou, et al.
Publicado: (2014) -
Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G
por: Hanjing Yang, et al.
Publicado: (2020) -
Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies.
por: Michael J Wichroski, et al.
Publicado: (2006)