Structural morphing in a symmetry-mismatched viral vertex

In icosahedral viruses, a symmetry-mismatched portal vertex is assembled by inserting a 12-fold-symmetric portal complex into a 5-fold-symmetric capsid environment. Here, the authors report a near-atomic-resolution in situ cryo-electron microscopy structure of this symmetrically mismatched viral ver...

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Autores principales: Qianglin Fang, Wei-Chun Tang, Pan Tao, Marthandan Mahalingam, Andrei Fokine, Michael G. Rossmann, Venigalla B. Rao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2e90a65facef4cc4a9de0b77b96d9c46
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spelling oai:doaj.org-article:2e90a65facef4cc4a9de0b77b96d9c462021-12-02T14:41:26ZStructural morphing in a symmetry-mismatched viral vertex10.1038/s41467-020-15575-42041-1723https://doaj.org/article/2e90a65facef4cc4a9de0b77b96d9c462020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15575-4https://doaj.org/toc/2041-1723In icosahedral viruses, a symmetry-mismatched portal vertex is assembled by inserting a 12-fold-symmetric portal complex into a 5-fold-symmetric capsid environment. Here, the authors report a near-atomic-resolution in situ cryo-electron microscopy structure of this symmetrically mismatched viral vertex from bacteriophage T4.Qianglin FangWei-Chun TangPan TaoMarthandan MahalingamAndrei FokineMichael G. RossmannVenigalla B. RaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qianglin Fang
Wei-Chun Tang
Pan Tao
Marthandan Mahalingam
Andrei Fokine
Michael G. Rossmann
Venigalla B. Rao
Structural morphing in a symmetry-mismatched viral vertex
description In icosahedral viruses, a symmetry-mismatched portal vertex is assembled by inserting a 12-fold-symmetric portal complex into a 5-fold-symmetric capsid environment. Here, the authors report a near-atomic-resolution in situ cryo-electron microscopy structure of this symmetrically mismatched viral vertex from bacteriophage T4.
format article
author Qianglin Fang
Wei-Chun Tang
Pan Tao
Marthandan Mahalingam
Andrei Fokine
Michael G. Rossmann
Venigalla B. Rao
author_facet Qianglin Fang
Wei-Chun Tang
Pan Tao
Marthandan Mahalingam
Andrei Fokine
Michael G. Rossmann
Venigalla B. Rao
author_sort Qianglin Fang
title Structural morphing in a symmetry-mismatched viral vertex
title_short Structural morphing in a symmetry-mismatched viral vertex
title_full Structural morphing in a symmetry-mismatched viral vertex
title_fullStr Structural morphing in a symmetry-mismatched viral vertex
title_full_unstemmed Structural morphing in a symmetry-mismatched viral vertex
title_sort structural morphing in a symmetry-mismatched viral vertex
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/2e90a65facef4cc4a9de0b77b96d9c46
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