Structural morphing in a symmetry-mismatched viral vertex
In icosahedral viruses, a symmetry-mismatched portal vertex is assembled by inserting a 12-fold-symmetric portal complex into a 5-fold-symmetric capsid environment. Here, the authors report a near-atomic-resolution in situ cryo-electron microscopy structure of this symmetrically mismatched viral ver...
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Nature Portfolio
2020
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oai:doaj.org-article:2e90a65facef4cc4a9de0b77b96d9c462021-12-02T14:41:26ZStructural morphing in a symmetry-mismatched viral vertex10.1038/s41467-020-15575-42041-1723https://doaj.org/article/2e90a65facef4cc4a9de0b77b96d9c462020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15575-4https://doaj.org/toc/2041-1723In icosahedral viruses, a symmetry-mismatched portal vertex is assembled by inserting a 12-fold-symmetric portal complex into a 5-fold-symmetric capsid environment. Here, the authors report a near-atomic-resolution in situ cryo-electron microscopy structure of this symmetrically mismatched viral vertex from bacteriophage T4.Qianglin FangWei-Chun TangPan TaoMarthandan MahalingamAndrei FokineMichael G. RossmannVenigalla B. RaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Qianglin Fang Wei-Chun Tang Pan Tao Marthandan Mahalingam Andrei Fokine Michael G. Rossmann Venigalla B. Rao Structural morphing in a symmetry-mismatched viral vertex |
description |
In icosahedral viruses, a symmetry-mismatched portal vertex is assembled by inserting a 12-fold-symmetric portal complex into a 5-fold-symmetric capsid environment. Here, the authors report a near-atomic-resolution in situ cryo-electron microscopy structure of this symmetrically mismatched viral vertex from bacteriophage T4. |
format |
article |
author |
Qianglin Fang Wei-Chun Tang Pan Tao Marthandan Mahalingam Andrei Fokine Michael G. Rossmann Venigalla B. Rao |
author_facet |
Qianglin Fang Wei-Chun Tang Pan Tao Marthandan Mahalingam Andrei Fokine Michael G. Rossmann Venigalla B. Rao |
author_sort |
Qianglin Fang |
title |
Structural morphing in a symmetry-mismatched viral vertex |
title_short |
Structural morphing in a symmetry-mismatched viral vertex |
title_full |
Structural morphing in a symmetry-mismatched viral vertex |
title_fullStr |
Structural morphing in a symmetry-mismatched viral vertex |
title_full_unstemmed |
Structural morphing in a symmetry-mismatched viral vertex |
title_sort |
structural morphing in a symmetry-mismatched viral vertex |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/2e90a65facef4cc4a9de0b77b96d9c46 |
work_keys_str_mv |
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_version_ |
1718389859813425152 |