Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors.

Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors.

An increasing number of malignancies has been shown to be initiated and propelled by small subpopulations of cancer stem cells (CSC). However, whether tumor aggressiveness is driven by CSC and by what extent this property may be relevant within the tumor mass is still unsettled. To address this issu...

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Main Authors: Luisa Salvatori, Francesca Caporuscio, Alessandra Verdina, Giuseppe Starace, Stefania Crispi, Maria Rita Nicotra, Andrea Russo, Raffaele Adolfo Calogero, Emanuela Morgante, Pier Giorgio Natali, Matteo Antonio Russo, Elisa Petrangeli
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/2e9f619025af45869b36cbbb61c84d80
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https://doaj.org/article/2e9f619025af45869b36cbbb61c84d80

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