Therapeutic Potential of MRGPRX2 Inhibitors on Mast Cells

Mast cells (MCs) act as primary effectors in inflammatory and allergic reactions by releasing intracellularly-stored inflammatory mediators in diseases. The two major pathways for MC activation are known to be immunoglobulin E (IgE)-dependent and -independent. Although IgE-dependent signaling is the...

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Bibliographic Details
Main Authors: Hiroyuki Ogasawara, Masato Noguchi
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/2ea13677bbc942228470c48136bd7146
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