A general approach to engineer positive-going eFRET voltage indicators
Genetically encoded voltage indicators (GEVIs) allow visualisation of fast action potentials in neurons but most are bright at rest and dimmer during an action potential. Here, the authors engineer electrochromic FRET GEVIs with fast, bright and positive-going fluorescence signals for in vivo imagin...
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Autores principales: | Ahmed S. Abdelfattah, Rosario Valenti, Jihong Zheng, Allan Wong, GENIE Project Team, Kaspar Podgorski, Minoru Koyama, Douglas S. Kim, Eric R. Schreiter |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/2ea2ff2c1bd44acdb9e04c2ab44cdf71 |
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