The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans

The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans

How dietary β-mannans are utilized by gut Gram-positive bacteria is unclear. Here, the authors uncover the enzymatic pathway for β-mannan metabolism in Roseburia intestinalis and show that these polysaccharides promote beneficial gut bacteria, highlighting a potential for β-mannan-based therapeutic...

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Autores principales: Sabina Leanti La Rosa, Maria Louise Leth, Leszek Michalak, Morten Ejby Hansen, Nicholas A. Pudlo, Robert Glowacki, Gabriel Pereira, Christopher T. Workman, Magnus Ø. Arntzen, Phillip B. Pope, Eric C. Martens, Maher Abou Hachem, Bjørge Westereng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2eb37bf7353c4750bb4b7813444df9b8
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spelling oai:doaj.org-article:2eb37bf7353c4750bb4b7813444df9b82021-12-02T15:35:37ZThe human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans10.1038/s41467-019-08812-y2041-1723https://doaj.org/article/2eb37bf7353c4750bb4b7813444df9b82019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08812-yhttps://doaj.org/toc/2041-1723How dietary β-mannans are utilized by gut Gram-positive bacteria is unclear. Here, the authors uncover the enzymatic pathway for β-mannan metabolism in Roseburia intestinalis and show that these polysaccharides promote beneficial gut bacteria, highlighting a potential for β-mannan-based therapeutic interventions.Sabina Leanti La RosaMaria Louise LethLeszek MichalakMorten Ejby HansenNicholas A. PudloRobert GlowackiGabriel PereiraChristopher T. WorkmanMagnus Ø. ArntzenPhillip B. PopeEric C. MartensMaher Abou HachemBjørge WesterengNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sabina Leanti La Rosa
Maria Louise Leth
Leszek Michalak
Morten Ejby Hansen
Nicholas A. Pudlo
Robert Glowacki
Gabriel Pereira
Christopher T. Workman
Magnus Ø. Arntzen
Phillip B. Pope
Eric C. Martens
Maher Abou Hachem
Bjørge Westereng
The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans
description How dietary β-mannans are utilized by gut Gram-positive bacteria is unclear. Here, the authors uncover the enzymatic pathway for β-mannan metabolism in Roseburia intestinalis and show that these polysaccharides promote beneficial gut bacteria, highlighting a potential for β-mannan-based therapeutic interventions.
format article
author Sabina Leanti La Rosa
Maria Louise Leth
Leszek Michalak
Morten Ejby Hansen
Nicholas A. Pudlo
Robert Glowacki
Gabriel Pereira
Christopher T. Workman
Magnus Ø. Arntzen
Phillip B. Pope
Eric C. Martens
Maher Abou Hachem
Bjørge Westereng
author_facet Sabina Leanti La Rosa
Maria Louise Leth
Leszek Michalak
Morten Ejby Hansen
Nicholas A. Pudlo
Robert Glowacki
Gabriel Pereira
Christopher T. Workman
Magnus Ø. Arntzen
Phillip B. Pope
Eric C. Martens
Maher Abou Hachem
Bjørge Westereng
author_sort Sabina Leanti La Rosa
title The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans
title_short The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans
title_full The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans
title_fullStr The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans
title_full_unstemmed The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans
title_sort human gut firmicute roseburia intestinalis is a primary degrader of dietary β-mannans
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/2eb37bf7353c4750bb4b7813444df9b8
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