Deletion of chromosomes 13q and 14q is a common feature of tumors with BRCA2 mutations.

Deletion of chromosomes 13q and 14q is a common feature of tumors with BRCA2 mutations.

<h4>Introduction</h4>Germline BRCA1 or BRCA2 mutations account for 20-30% of familial clustering of breast cancer. The main indication for BRCA2 screening is currently the family history but the yield of mutations identified in patients selected this way is low.<h4>Methods</h4&g...

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Autores principales: Audrey Rouault, Guillaume Banneau, Gaëtan Macgrogan, Natalie Jones, Nabila Elarouci, Emmanuelle Barouk-Simonet, Laurence Venat, Isabelle Coupier, Eric Letouzé, Aurélien de Reyniès, Françoise Bonnet, Richard Iggo, Nicolas Sévenet, Michel Longy
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2eb48b9506784ef49d11558558e0dc62
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