VEGFR2 signaling drives meningeal vascular regeneration upon head injury

Severe head injury results in critical damage of blood vessels of the meninges and brain parenchyma. Here, the authors describe key pathways governing meningeal vascular regeneration following head injury, characterizing the differential roles of VEGFR2, Tie2, Dll4 and PDGFRβ signaling.

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Detalles Bibliográficos
Autores principales: Bong Ihn Koh, Hyuek Jong Lee, Pil Ae Kwak, Myung Jin Yang, Ju-Hee Kim, Hyung-Seok Kim, Gou Young Koh, Injune Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2eb4ae02c0ec45c493c733e63d569b0b
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Sumario:Severe head injury results in critical damage of blood vessels of the meninges and brain parenchyma. Here, the authors describe key pathways governing meningeal vascular regeneration following head injury, characterizing the differential roles of VEGFR2, Tie2, Dll4 and PDGFRβ signaling.