VEGFR2 signaling drives meningeal vascular regeneration upon head injury
Severe head injury results in critical damage of blood vessels of the meninges and brain parenchyma. Here, the authors describe key pathways governing meningeal vascular regeneration following head injury, characterizing the differential roles of VEGFR2, Tie2, Dll4 and PDGFRβ signaling.
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Nature Portfolio
2020
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oai:doaj.org-article:2eb4ae02c0ec45c493c733e63d569b0b2021-12-02T16:24:53ZVEGFR2 signaling drives meningeal vascular regeneration upon head injury10.1038/s41467-020-17545-22041-1723https://doaj.org/article/2eb4ae02c0ec45c493c733e63d569b0b2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17545-2https://doaj.org/toc/2041-1723Severe head injury results in critical damage of blood vessels of the meninges and brain parenchyma. Here, the authors describe key pathways governing meningeal vascular regeneration following head injury, characterizing the differential roles of VEGFR2, Tie2, Dll4 and PDGFRβ signaling.Bong Ihn KohHyuek Jong LeePil Ae KwakMyung Jin YangJu-Hee KimHyung-Seok KimGou Young KohInjune KimNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
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Science Q Bong Ihn Koh Hyuek Jong Lee Pil Ae Kwak Myung Jin Yang Ju-Hee Kim Hyung-Seok Kim Gou Young Koh Injune Kim VEGFR2 signaling drives meningeal vascular regeneration upon head injury |
description |
Severe head injury results in critical damage of blood vessels of the meninges and brain parenchyma. Here, the authors describe key pathways governing meningeal vascular regeneration following head injury, characterizing the differential roles of VEGFR2, Tie2, Dll4 and PDGFRβ signaling. |
format |
article |
author |
Bong Ihn Koh Hyuek Jong Lee Pil Ae Kwak Myung Jin Yang Ju-Hee Kim Hyung-Seok Kim Gou Young Koh Injune Kim |
author_facet |
Bong Ihn Koh Hyuek Jong Lee Pil Ae Kwak Myung Jin Yang Ju-Hee Kim Hyung-Seok Kim Gou Young Koh Injune Kim |
author_sort |
Bong Ihn Koh |
title |
VEGFR2 signaling drives meningeal vascular regeneration upon head injury |
title_short |
VEGFR2 signaling drives meningeal vascular regeneration upon head injury |
title_full |
VEGFR2 signaling drives meningeal vascular regeneration upon head injury |
title_fullStr |
VEGFR2 signaling drives meningeal vascular regeneration upon head injury |
title_full_unstemmed |
VEGFR2 signaling drives meningeal vascular regeneration upon head injury |
title_sort |
vegfr2 signaling drives meningeal vascular regeneration upon head injury |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/2eb4ae02c0ec45c493c733e63d569b0b |
work_keys_str_mv |
AT bongihnkoh vegfr2signalingdrivesmeningealvascularregenerationuponheadinjury AT hyuekjonglee vegfr2signalingdrivesmeningealvascularregenerationuponheadinjury AT pilaekwak vegfr2signalingdrivesmeningealvascularregenerationuponheadinjury AT myungjinyang vegfr2signalingdrivesmeningealvascularregenerationuponheadinjury AT juheekim vegfr2signalingdrivesmeningealvascularregenerationuponheadinjury AT hyungseokkim vegfr2signalingdrivesmeningealvascularregenerationuponheadinjury AT gouyoungkoh vegfr2signalingdrivesmeningealvascularregenerationuponheadinjury AT injunekim vegfr2signalingdrivesmeningealvascularregenerationuponheadinjury |
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1718384101087510528 |