Ultra-long-acting removable drug delivery system for HIV treatment and prevention

Long-acting (LA) formulations of antiretroviral (ARV) drugs are an alternative approach to improve adherence for HIV treatment and prevention. Here the authors show a removable biodegradable ultra-LA-ARV drug system that effectively delivers drug, controls viremia and prevents infection in animal mo...

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Autores principales: Martina Kovarova, S. Rahima Benhabbour, Ivana Massud, Rae Ann Spagnuolo, Brianna Skinner, Caroline E. Baker, Craig Sykes, Katie R. Mollan, Angela D. M. Kashuba, J. Gerardo García-Lerma, Russell J. Mumper, J. Victor Garcia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2eb550bf31b74367b1026c950200b662
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Sumario:Long-acting (LA) formulations of antiretroviral (ARV) drugs are an alternative approach to improve adherence for HIV treatment and prevention. Here the authors show a removable biodegradable ultra-LA-ARV drug system that effectively delivers drug, controls viremia and prevents infection in animal models of HIV infection.