Ultra-long-acting removable drug delivery system for HIV treatment and prevention

Long-acting (LA) formulations of antiretroviral (ARV) drugs are an alternative approach to improve adherence for HIV treatment and prevention. Here the authors show a removable biodegradable ultra-LA-ARV drug system that effectively delivers drug, controls viremia and prevents infection in animal mo...

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Autores principales: Martina Kovarova, S. Rahima Benhabbour, Ivana Massud, Rae Ann Spagnuolo, Brianna Skinner, Caroline E. Baker, Craig Sykes, Katie R. Mollan, Angela D. M. Kashuba, J. Gerardo García-Lerma, Russell J. Mumper, J. Victor Garcia
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2eb550bf31b74367b1026c950200b662
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spelling oai:doaj.org-article:2eb550bf31b74367b1026c950200b6622021-12-02T17:31:32ZUltra-long-acting removable drug delivery system for HIV treatment and prevention10.1038/s41467-018-06490-w2041-1723https://doaj.org/article/2eb550bf31b74367b1026c950200b6622018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06490-whttps://doaj.org/toc/2041-1723Long-acting (LA) formulations of antiretroviral (ARV) drugs are an alternative approach to improve adherence for HIV treatment and prevention. Here the authors show a removable biodegradable ultra-LA-ARV drug system that effectively delivers drug, controls viremia and prevents infection in animal models of HIV infection.Martina KovarovaS. Rahima BenhabbourIvana MassudRae Ann SpagnuoloBrianna SkinnerCaroline E. BakerCraig SykesKatie R. MollanAngela D. M. KashubaJ. Gerardo García-LermaRussell J. MumperJ. Victor GarciaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Martina Kovarova
S. Rahima Benhabbour
Ivana Massud
Rae Ann Spagnuolo
Brianna Skinner
Caroline E. Baker
Craig Sykes
Katie R. Mollan
Angela D. M. Kashuba
J. Gerardo García-Lerma
Russell J. Mumper
J. Victor Garcia
Ultra-long-acting removable drug delivery system for HIV treatment and prevention
description Long-acting (LA) formulations of antiretroviral (ARV) drugs are an alternative approach to improve adherence for HIV treatment and prevention. Here the authors show a removable biodegradable ultra-LA-ARV drug system that effectively delivers drug, controls viremia and prevents infection in animal models of HIV infection.
format article
author Martina Kovarova
S. Rahima Benhabbour
Ivana Massud
Rae Ann Spagnuolo
Brianna Skinner
Caroline E. Baker
Craig Sykes
Katie R. Mollan
Angela D. M. Kashuba
J. Gerardo García-Lerma
Russell J. Mumper
J. Victor Garcia
author_facet Martina Kovarova
S. Rahima Benhabbour
Ivana Massud
Rae Ann Spagnuolo
Brianna Skinner
Caroline E. Baker
Craig Sykes
Katie R. Mollan
Angela D. M. Kashuba
J. Gerardo García-Lerma
Russell J. Mumper
J. Victor Garcia
author_sort Martina Kovarova
title Ultra-long-acting removable drug delivery system for HIV treatment and prevention
title_short Ultra-long-acting removable drug delivery system for HIV treatment and prevention
title_full Ultra-long-acting removable drug delivery system for HIV treatment and prevention
title_fullStr Ultra-long-acting removable drug delivery system for HIV treatment and prevention
title_full_unstemmed Ultra-long-acting removable drug delivery system for HIV treatment and prevention
title_sort ultra-long-acting removable drug delivery system for hiv treatment and prevention
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/2eb550bf31b74367b1026c950200b662
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