<i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection

Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowled...

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Autores principales: Helena Strand Clemmensen, Jean-Yves Dube, Fiona McIntosh, Ida Rosenkrands, Gregers Jungersen, Claus Aagaard, Peter Andersen, Marcel A. Behr, Rasmus Mortensen
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/2ebf09603932441099af75020674a1ba
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spelling oai:doaj.org-article:2ebf09603932441099af75020674a1ba2021-11-03T18:56:09Z <i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection 2150-751110.1128/mBio.00226-21https://doaj.org/article/2ebf09603932441099af75020674a1ba2021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00226-21https://doaj.org/toc/2150-7511 Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development.Helena Strand ClemmensenJean-Yves DubeFiona McIntoshIda RosenkrandsGregers JungersenClaus AagaardPeter AndersenMarcel A. BehrRasmus MortensenAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Helena Strand Clemmensen
Jean-Yves Dube
Fiona McIntosh
Ida Rosenkrands
Gregers Jungersen
Claus Aagaard
Peter Andersen
Marcel A. Behr
Rasmus Mortensen
<i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection
description Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development.
format article
author Helena Strand Clemmensen
Jean-Yves Dube
Fiona McIntosh
Ida Rosenkrands
Gregers Jungersen
Claus Aagaard
Peter Andersen
Marcel A. Behr
Rasmus Mortensen
author_facet Helena Strand Clemmensen
Jean-Yves Dube
Fiona McIntosh
Ida Rosenkrands
Gregers Jungersen
Claus Aagaard
Peter Andersen
Marcel A. Behr
Rasmus Mortensen
author_sort Helena Strand Clemmensen
title <i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection
title_short <i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection
title_full <i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection
title_fullStr <i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection
title_full_unstemmed <i>In Vivo</i> Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection
title_sort <i>in vivo</i> antigen expression regulates cd4 t cell differentiation and vaccine efficacy against mycobacterium tuberculosis infection
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/2ebf09603932441099af75020674a1ba
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