Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface

During tumor progression, cancer cells contact different neighboring cell types, but it is unclear how these interactions affect cancer cell behavior. Here, the authors use spatially resolved transcriptomics and single-cell RNA-seq to study the role of cilia at the tumormicroenvironment interface.

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Detalles Bibliográficos
Autores principales:	Miranda V. Hunter, Reuben Moncada, Joshua M. Weiss, Itai Yanai, Richard M. White
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2ecde4c51693444e848693a8ceaca4c3
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spelling	oai:doaj.org-article:2ecde4c51693444e848693a8ceaca4c32021-11-08T11:07:25ZSpatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface10.1038/s41467-021-26614-z2041-1723https://doaj.org/article/2ecde4c51693444e848693a8ceaca4c32021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26614-zhttps://doaj.org/toc/2041-1723During tumor progression, cancer cells contact different neighboring cell types, but it is unclear how these interactions affect cancer cell behavior. Here, the authors use spatially resolved transcriptomics and single-cell RNA-seq to study the role of cilia at the tumormicroenvironment interface.Miranda V. HunterReuben MoncadaJoshua M. WeissItai YanaiRichard M. WhiteNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Miranda V. Hunter Reuben Moncada Joshua M. Weiss Itai Yanai Richard M. White Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
description	During tumor progression, cancer cells contact different neighboring cell types, but it is unclear how these interactions affect cancer cell behavior. Here, the authors use spatially resolved transcriptomics and single-cell RNA-seq to study the role of cilia at the tumormicroenvironment interface.
format	article
author	Miranda V. Hunter Reuben Moncada Joshua M. Weiss Itai Yanai Richard M. White
author_facet	Miranda V. Hunter Reuben Moncada Joshua M. Weiss Itai Yanai Richard M. White
author_sort	Miranda V. Hunter
title	Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
title_short	Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
title_full	Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
title_fullStr	Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
title_full_unstemmed	Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
title_sort	spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2ecde4c51693444e848693a8ceaca4c3
work_keys_str_mv	AT mirandavhunter spatiallyresolvedtranscriptomicsrevealsthearchitectureofthetumormicroenvironmentinterface AT reubenmoncada spatiallyresolvedtranscriptomicsrevealsthearchitectureofthetumormicroenvironmentinterface AT joshuamweiss spatiallyresolvedtranscriptomicsrevealsthearchitectureofthetumormicroenvironmentinterface AT itaiyanai spatiallyresolvedtranscriptomicsrevealsthearchitectureofthetumormicroenvironmentinterface AT richardmwhite spatiallyresolvedtranscriptomicsrevealsthearchitectureofthetumormicroenvironmentinterface
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Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface

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