Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica.

Although lipopolysaccharide (LPS) stimulation through the Toll-like receptor (TLR)-4/MD-2 receptor complex activates host defense against Gram-negative bacterial pathogens, how species-specific differences in LPS recognition impact host defense remains undefined. Herein, we establish how temperature...

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Autores principales: Adeline M Hajjar, Robert K Ernst, Edgardo S Fortuno, Alicia S Brasfield, Cathy S Yam, Lindsay A Newlon, Tobias R Kollmann, Samuel I Miller, Christopher B Wilson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/2ed58c4147da46e883f07ede1e6adae8
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