A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells
Many cancer cells have increased glucose consumption compared to normal cells, a feature that can be exploited therapeutically. Here, the authors carry out a chemical screen and identify compounds that selectively blocks glucose metabolism in non-small-cell lung cancer cell lines.
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Auteurs principaux: | Chiara Ghezzi, Alicia Wong, Bao Ying Chen, Bernard Ribalet, Robert Damoiseaux, Peter M. Clark |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Sujets: | |
Accès en ligne: | https://doaj.org/article/2eda619824de42219eeab1b51ef3beb0 |
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