The Systemic Response to Topical Aldara Treatment is Mediated Through Direct TLR7 Stimulation as Imiquimod Enters the Circulation
Abstract Topical application of Aldara cream, containing the Toll-like receptor 7/8 agonist Imiquimod, is a widely used mouse model for investigating the pathogenesis of psoriasis. We have previously used this model to study the effects of peripheral inflammation on the brain, and reported a brain-s...
Guardado en:
Autores principales: | Louis Nerurkar, Alison McColl, Gerard Graham, Jonathan Cavanagh |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2ee0e4bef1594738b6d440d38972e7be |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The TLR7 agonist Imiquimod promote the immunogenicity of msenchymal stem cells
por: Zhang,Li, et al.
Publicado: (2015) -
Advances in the use of topical imiquimod to treat dermatologic disorders
por: Francesco Lacarrubba, et al.
Publicado: (2008) -
First-line therapy for human cutaneous leishmaniasis in Peru using the TLR7 agonist imiquimod in combination with pentavalent antimony.
por: Cesar Miranda-Verastegui, et al.
Publicado: (2009) -
Usefulness of Topical Imiquimod 3.75% in Cytokeratin 7 Positive Extramammary Paget Disease of the Vulva: Towards Personalized Therapy
por: Sara Mazzilli, et al.
Publicado: (2021) -
Successful treatment of a keratoacanthoma in a young patient with the application of topical 5% imiquimod cream
por: Kerasia‐Maria Plachouri, et al.
Publicado: (2021)