Functional promoter -308G>A variant in tumor necrosis factor α gene is associated with risk and progression of gastric cancer in a Chinese population.

<h4>Background</h4>Tumor necrosis factor-α (TNF-α) plays a crucial role in the development and progression of gastric cancer. A functional polymorphism, -308 G>A (rs1800629), which is located in the promoter of TNFA gene, has been suggested to alter the production of TNF-α and influen...

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Main Authors: Yan Hong, Zhijun Ge, Changrui Jing, Jun Shi, Xiao Dong, Fengying Zhou, Meilin Wang, Zhengdong Zhang, Weida Gong
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/2ee55835dab14ed98d2e45b0b13293be
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