Functional promoter -308G>A variant in tumor necrosis factor α gene is associated with risk and progression of gastric cancer in a Chinese population.
<h4>Background</h4>Tumor necrosis factor-α (TNF-α) plays a crucial role in the development and progression of gastric cancer. A functional polymorphism, -308 G>A (rs1800629), which is located in the promoter of TNFA gene, has been suggested to alter the production of TNF-α and influen...
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Autores principales: | Yan Hong, Zhijun Ge, Changrui Jing, Jun Shi, Xiao Dong, Fengying Zhou, Meilin Wang, Zhengdong Zhang, Weida Gong |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/2ee55835dab14ed98d2e45b0b13293be |
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