A rare cause of postpartum vaginal bleeding

Abstract Background Invasive mole is a trophoblastic disease (GTD) caused by trophoblast cells invading the myometrium during pregnancy. The GTD range also includes mole hydatidiform, choriocarcinoma, and placental site trophoblastic tumor (PSTT). Invasive moles are most common following molar pregn...

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Autores principales:	Oğuzhan Tokur, Sonay Aydın, Erdem Fatihoğlu, Fatma Dilek Gökharman
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Gestational trophoblastic disease (GTD) Invasive mole Healthy pregnancy Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/2ee9ea3c464a4962a0f56aabb8ab7ad1
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spelling	oai:doaj.org-article:2ee9ea3c464a4962a0f56aabb8ab7ad12021-11-28T12:23:23ZA rare cause of postpartum vaginal bleeding10.1186/s43055-021-00666-z2090-4762https://doaj.org/article/2ee9ea3c464a4962a0f56aabb8ab7ad12021-11-01T00:00:00Zhttps://doi.org/10.1186/s43055-021-00666-zhttps://doaj.org/toc/2090-4762Abstract Background Invasive mole is a trophoblastic disease (GTD) caused by trophoblast cells invading the myometrium during pregnancy. The GTD range also includes mole hydatidiform, choriocarcinoma, and placental site trophoblastic tumor (PSTT). Invasive moles are most common following molar pregnancies; however, they can even rarely occur after a full-term birth. Despite the fact that pathology is the only way to make a clear diagnosis, clinic and radiologic evaluation can be helpful. We wanted to highlight a rare incidence of invasive mole following a healthy full-term delivery in this case. Case presentation A 28-year-old female patient presented with intermittent prolonged severe vaginal bleeding for 2 weeks after a term healthy vaginal delivery. In workup, beta human chorionic gonadotropin levels (b-hCG) value was 7540 mIU/ml. After suspicion of gestational trophoblastic neoplasm (GTN), the patient was sent to ultrasonography (US) and magnetic resonance imaging (MRI). GTN was confirmed by radiological and clinical findings, and a conclusive diagnosis of an invasive mole was made histopathologically. Conclusion Invasive mole should be considered in the differential diagnosis in patients with postpartum bleeding and a persistently high b-hCG level after a healthy term delivery.Oğuzhan TokurSonay AydınErdem FatihoğluFatma Dilek GökharmanSpringerOpenarticleGestational trophoblastic disease (GTD)Invasive moleHealthy pregnancyMedical physics. Medical radiology. Nuclear medicineR895-920ENThe Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Gestational trophoblastic disease (GTD) Invasive mole Healthy pregnancy Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	Gestational trophoblastic disease (GTD) Invasive mole Healthy pregnancy Medical physics. Medical radiology. Nuclear medicine R895-920 Oğuzhan Tokur Sonay Aydın Erdem Fatihoğlu Fatma Dilek Gökharman A rare cause of postpartum vaginal bleeding
description	Abstract Background Invasive mole is a trophoblastic disease (GTD) caused by trophoblast cells invading the myometrium during pregnancy. The GTD range also includes mole hydatidiform, choriocarcinoma, and placental site trophoblastic tumor (PSTT). Invasive moles are most common following molar pregnancies; however, they can even rarely occur after a full-term birth. Despite the fact that pathology is the only way to make a clear diagnosis, clinic and radiologic evaluation can be helpful. We wanted to highlight a rare incidence of invasive mole following a healthy full-term delivery in this case. Case presentation A 28-year-old female patient presented with intermittent prolonged severe vaginal bleeding for 2 weeks after a term healthy vaginal delivery. In workup, beta human chorionic gonadotropin levels (b-hCG) value was 7540 mIU/ml. After suspicion of gestational trophoblastic neoplasm (GTN), the patient was sent to ultrasonography (US) and magnetic resonance imaging (MRI). GTN was confirmed by radiological and clinical findings, and a conclusive diagnosis of an invasive mole was made histopathologically. Conclusion Invasive mole should be considered in the differential diagnosis in patients with postpartum bleeding and a persistently high b-hCG level after a healthy term delivery.
format	article
author	Oğuzhan Tokur Sonay Aydın Erdem Fatihoğlu Fatma Dilek Gökharman
author_facet	Oğuzhan Tokur Sonay Aydın Erdem Fatihoğlu Fatma Dilek Gökharman
author_sort	Oğuzhan Tokur
title	A rare cause of postpartum vaginal bleeding
title_short	A rare cause of postpartum vaginal bleeding
title_full	A rare cause of postpartum vaginal bleeding
title_fullStr	A rare cause of postpartum vaginal bleeding
title_full_unstemmed	A rare cause of postpartum vaginal bleeding
title_sort	rare cause of postpartum vaginal bleeding
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/2ee9ea3c464a4962a0f56aabb8ab7ad1
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A rare cause of postpartum vaginal bleeding

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