A coordinated progression of progenitor cell states initiates urinary tract development

Nephric duct (ND)-derived ureteric buds (UB) form the kidney collecting duct system, while ureteric tips promote nephron formation. Here the authors use single-cell RNA-seq and introduce Cluster RNA-seq to identify four progenitor populations in developing ND/UB regulated by the transcription factor...

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Autores principales: Oraly Sanchez-Ferras, Alain Pacis, Maria Sotiropoulou, Yuhong Zhang, Yu Chang Wang, Mathieu Bourgey, Guillaume Bourque, Jiannis Ragoussis, Maxime Bouchard
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2ef679d5c21a4d05af1a81f482877344
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spelling oai:doaj.org-article:2ef679d5c21a4d05af1a81f4828773442021-12-02T16:57:56ZA coordinated progression of progenitor cell states initiates urinary tract development10.1038/s41467-021-22931-52041-1723https://doaj.org/article/2ef679d5c21a4d05af1a81f4828773442021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22931-5https://doaj.org/toc/2041-1723Nephric duct (ND)-derived ureteric buds (UB) form the kidney collecting duct system, while ureteric tips promote nephron formation. Here the authors use single-cell RNA-seq and introduce Cluster RNA-seq to identify four progenitor populations in developing ND/UB regulated by the transcription factors Tfap2a/b and Gata3.Oraly Sanchez-FerrasAlain PacisMaria SotiropoulouYuhong ZhangYu Chang WangMathieu BourgeyGuillaume BourqueJiannis RagoussisMaxime BouchardNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Oraly Sanchez-Ferras
Alain Pacis
Maria Sotiropoulou
Yuhong Zhang
Yu Chang Wang
Mathieu Bourgey
Guillaume Bourque
Jiannis Ragoussis
Maxime Bouchard
A coordinated progression of progenitor cell states initiates urinary tract development
description Nephric duct (ND)-derived ureteric buds (UB) form the kidney collecting duct system, while ureteric tips promote nephron formation. Here the authors use single-cell RNA-seq and introduce Cluster RNA-seq to identify four progenitor populations in developing ND/UB regulated by the transcription factors Tfap2a/b and Gata3.
format article
author Oraly Sanchez-Ferras
Alain Pacis
Maria Sotiropoulou
Yuhong Zhang
Yu Chang Wang
Mathieu Bourgey
Guillaume Bourque
Jiannis Ragoussis
Maxime Bouchard
author_facet Oraly Sanchez-Ferras
Alain Pacis
Maria Sotiropoulou
Yuhong Zhang
Yu Chang Wang
Mathieu Bourgey
Guillaume Bourque
Jiannis Ragoussis
Maxime Bouchard
author_sort Oraly Sanchez-Ferras
title A coordinated progression of progenitor cell states initiates urinary tract development
title_short A coordinated progression of progenitor cell states initiates urinary tract development
title_full A coordinated progression of progenitor cell states initiates urinary tract development
title_fullStr A coordinated progression of progenitor cell states initiates urinary tract development
title_full_unstemmed A coordinated progression of progenitor cell states initiates urinary tract development
title_sort coordinated progression of progenitor cell states initiates urinary tract development
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/2ef679d5c21a4d05af1a81f482877344
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