A coordinated progression of progenitor cell states initiates urinary tract development
Nephric duct (ND)-derived ureteric buds (UB) form the kidney collecting duct system, while ureteric tips promote nephron formation. Here the authors use single-cell RNA-seq and introduce Cluster RNA-seq to identify four progenitor populations in developing ND/UB regulated by the transcription factor...
Guardado en:
Autores principales: | , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2ef679d5c21a4d05af1a81f482877344 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:2ef679d5c21a4d05af1a81f482877344 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:2ef679d5c21a4d05af1a81f4828773442021-12-02T16:57:56ZA coordinated progression of progenitor cell states initiates urinary tract development10.1038/s41467-021-22931-52041-1723https://doaj.org/article/2ef679d5c21a4d05af1a81f4828773442021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22931-5https://doaj.org/toc/2041-1723Nephric duct (ND)-derived ureteric buds (UB) form the kidney collecting duct system, while ureteric tips promote nephron formation. Here the authors use single-cell RNA-seq and introduce Cluster RNA-seq to identify four progenitor populations in developing ND/UB regulated by the transcription factors Tfap2a/b and Gata3.Oraly Sanchez-FerrasAlain PacisMaria SotiropoulouYuhong ZhangYu Chang WangMathieu BourgeyGuillaume BourqueJiannis RagoussisMaxime BouchardNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Oraly Sanchez-Ferras Alain Pacis Maria Sotiropoulou Yuhong Zhang Yu Chang Wang Mathieu Bourgey Guillaume Bourque Jiannis Ragoussis Maxime Bouchard A coordinated progression of progenitor cell states initiates urinary tract development |
description |
Nephric duct (ND)-derived ureteric buds (UB) form the kidney collecting duct system, while ureteric tips promote nephron formation. Here the authors use single-cell RNA-seq and introduce Cluster RNA-seq to identify four progenitor populations in developing ND/UB regulated by the transcription factors Tfap2a/b and Gata3. |
format |
article |
author |
Oraly Sanchez-Ferras Alain Pacis Maria Sotiropoulou Yuhong Zhang Yu Chang Wang Mathieu Bourgey Guillaume Bourque Jiannis Ragoussis Maxime Bouchard |
author_facet |
Oraly Sanchez-Ferras Alain Pacis Maria Sotiropoulou Yuhong Zhang Yu Chang Wang Mathieu Bourgey Guillaume Bourque Jiannis Ragoussis Maxime Bouchard |
author_sort |
Oraly Sanchez-Ferras |
title |
A coordinated progression of progenitor cell states initiates urinary tract development |
title_short |
A coordinated progression of progenitor cell states initiates urinary tract development |
title_full |
A coordinated progression of progenitor cell states initiates urinary tract development |
title_fullStr |
A coordinated progression of progenitor cell states initiates urinary tract development |
title_full_unstemmed |
A coordinated progression of progenitor cell states initiates urinary tract development |
title_sort |
coordinated progression of progenitor cell states initiates urinary tract development |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/2ef679d5c21a4d05af1a81f482877344 |
work_keys_str_mv |
AT oralysanchezferras acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT alainpacis acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT mariasotiropoulou acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT yuhongzhang acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT yuchangwang acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT mathieubourgey acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT guillaumebourque acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT jiannisragoussis acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT maximebouchard acoordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT oralysanchezferras coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT alainpacis coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT mariasotiropoulou coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT yuhongzhang coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT yuchangwang coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT mathieubourgey coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT guillaumebourque coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT jiannisragoussis coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment AT maximebouchard coordinatedprogressionofprogenitorcellstatesinitiatesurinarytractdevelopment |
_version_ |
1718382438459113472 |