Three dimensional two-photon brain imaging in freely moving mice using a miniature fiber coupled microscope with active axial-scanning

Abstract We present a miniature head mounted two-photon fiber-coupled microscope (2P-FCM) for neuronal imaging with active axial focusing enabled using a miniature electrowetting lens. We show three-dimensional two-photon imaging of neuronal structure and record neuronal activity from GCaMP6s fluore...

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Bibliographic Details
Main Authors: Baris N. Ozbay, Gregory L. Futia, Ming Ma, Victor M. Bright, Juliet T. Gopinath, Ethan G. Hughes, Diego Restrepo, Emily A. Gibson
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/2ef9a8fab2784af381b67b48283922d0
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