OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology

The efficiency of preclinical drug testing and characterization of cellular function can be improved through the use of optogenetic tools. Here Klimas et al. present and validate OptoDyCE, a fully automated system for all-optical high-throughput cardiac electrophysiology.

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Autores principales: Aleksandra Klimas, Christina M. Ambrosi, Jinzhu Yu, John C. Williams, Harold Bien, Emilia Entcheva
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/2f045d59790a4de5927733565d3a97ad
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spelling oai:doaj.org-article:2f045d59790a4de5927733565d3a97ad2021-12-02T17:33:08ZOptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology10.1038/ncomms115422041-1723https://doaj.org/article/2f045d59790a4de5927733565d3a97ad2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11542https://doaj.org/toc/2041-1723The efficiency of preclinical drug testing and characterization of cellular function can be improved through the use of optogenetic tools. Here Klimas et al. present and validate OptoDyCE, a fully automated system for all-optical high-throughput cardiac electrophysiology.Aleksandra KlimasChristina M. AmbrosiJinzhu YuJohn C. WilliamsHarold BienEmilia EntchevaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aleksandra Klimas
Christina M. Ambrosi
Jinzhu Yu
John C. Williams
Harold Bien
Emilia Entcheva
OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
description The efficiency of preclinical drug testing and characterization of cellular function can be improved through the use of optogenetic tools. Here Klimas et al. present and validate OptoDyCE, a fully automated system for all-optical high-throughput cardiac electrophysiology.
format article
author Aleksandra Klimas
Christina M. Ambrosi
Jinzhu Yu
John C. Williams
Harold Bien
Emilia Entcheva
author_facet Aleksandra Klimas
Christina M. Ambrosi
Jinzhu Yu
John C. Williams
Harold Bien
Emilia Entcheva
author_sort Aleksandra Klimas
title OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
title_short OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
title_full OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
title_fullStr OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
title_full_unstemmed OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
title_sort optodyce as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/2f045d59790a4de5927733565d3a97ad
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AT jinzhuyu optodyceasanautomatedsystemforhighthroughputallopticaldynamiccardiacelectrophysiology
AT johncwilliams optodyceasanautomatedsystemforhighthroughputallopticaldynamiccardiacelectrophysiology
AT haroldbien optodyceasanautomatedsystemforhighthroughputallopticaldynamiccardiacelectrophysiology
AT emiliaentcheva optodyceasanautomatedsystemforhighthroughputallopticaldynamiccardiacelectrophysiology
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