OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
The efficiency of preclinical drug testing and characterization of cellular function can be improved through the use of optogenetic tools. Here Klimas et al. present and validate OptoDyCE, a fully automated system for all-optical high-throughput cardiac electrophysiology.
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Nature Portfolio
2016
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oai:doaj.org-article:2f045d59790a4de5927733565d3a97ad2021-12-02T17:33:08ZOptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology10.1038/ncomms115422041-1723https://doaj.org/article/2f045d59790a4de5927733565d3a97ad2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11542https://doaj.org/toc/2041-1723The efficiency of preclinical drug testing and characterization of cellular function can be improved through the use of optogenetic tools. Here Klimas et al. present and validate OptoDyCE, a fully automated system for all-optical high-throughput cardiac electrophysiology.Aleksandra KlimasChristina M. AmbrosiJinzhu YuJohn C. WilliamsHarold BienEmilia EntchevaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016) |
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Science Q Aleksandra Klimas Christina M. Ambrosi Jinzhu Yu John C. Williams Harold Bien Emilia Entcheva OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology |
description |
The efficiency of preclinical drug testing and characterization of cellular function can be improved through the use of optogenetic tools. Here Klimas et al. present and validate OptoDyCE, a fully automated system for all-optical high-throughput cardiac electrophysiology. |
format |
article |
author |
Aleksandra Klimas Christina M. Ambrosi Jinzhu Yu John C. Williams Harold Bien Emilia Entcheva |
author_facet |
Aleksandra Klimas Christina M. Ambrosi Jinzhu Yu John C. Williams Harold Bien Emilia Entcheva |
author_sort |
Aleksandra Klimas |
title |
OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology |
title_short |
OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology |
title_full |
OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology |
title_fullStr |
OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology |
title_full_unstemmed |
OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology |
title_sort |
optodyce as an automated system for high-throughput all-optical dynamic cardiac electrophysiology |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/2f045d59790a4de5927733565d3a97ad |
work_keys_str_mv |
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