Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients

Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients

Abstract Carboxylesterase 1 (CES1) hydrolyzes the prodrug clopidogrel to an inactive carboxylic acid metabolite. The effects of CES1 S75N (rs2307240,C>T) on clopidogrel response among 851 acute coronary syndrome patients who came from the north, central and south of China were studied. The occurr...

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Autores principales: Fei-Yan Xiao, Jian-Quan Luo, Min Liu, Bi-Lian Chen, Shan Cao, Zhao-Qian Liu, Hong-Hao Zhou, Gan Zhou, Wei Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/2f0529fa67884af39b5ca50b417bbf92
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