Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2
Risk for the paediatric cancer high-hyperdiploid acute lymphoblastic leukaemia (HD-ALL) has been associated with genetic variants at 10q21.2. Here, the authors characterize this region, establishing a single risk variant and showing its role in dysregulated expression ofARID5B.
Guardado en:
Autores principales: | James B. Studd, Jayaram Vijayakrishnan, Minjun Yang, Gabriele Migliorini, Kajsa Paulsson, Richard S. Houlston |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2f05a5509ae64698a25e08892abeb315 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Correction: Author Correction: Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10q21.2
por: James B. Studd, et al.
Publicado: (2018) -
Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia
por: Minjun Yang, et al.
Publicado: (2019) -
Cancer drivers and clonal dynamics in acute lymphoblastic leukaemia subtypes
por: James B. Studd, et al.
Publicado: (2021) -
Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk
por: Jayaram Vijayakrishnan, et al.
Publicado: (2019) -
Osteonecrosis as the presenting feature in a child with acute lymphoblastic leukaemia
por: Lim Sern Chin, et al.
Publicado: (2021)