A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system

Abstract Gene therapy revolves around modifying genetic makeup by inserting foreign nucleic acids into targeted cells via gene delivery methods to treat a particular disease. While the genes targeted play a key role in gene therapy, the gene delivery system used is also of utmost importance as it de...

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Autores principales: V. Kalidasan, Wai Hoe Ng, Oluwaseun Ayodeji Ishola, Nithya Ravichantar, Jun Jie Tan, Kumitaa Theva Das
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2f0a52a5611d43b2989a84073a2f6158
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