Beyond Toxin Transport: Novel Role of ABC Transporter for Enzymatic Machinery of Cereulide NRPS Assembly Line
ABSTRACT Nonribosomal peptide synthetases (NRPSs) and polyketide synthetases (PKSs) play a pivotal role in the production of bioactive natural products, such as antibiotics and cytotoxins. Despite biomedical and pharmaceutical importance, the molecular mechanisms and architectures of these multimodu...
Enregistré dans:
Auteurs principaux: | A. Gacek-Matthews, Z. Chromiková, M. Sulyok, G. Lücking, I. Barák, M. Ehling-Schulz |
---|---|
Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2020
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/2f185f66f2b14acda99479261788cd65 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Cereulide Synthetase Acquisition and Loss Events within the Evolutionary History of Group III <italic toggle="yes">Bacillus cereus Sensu Lato</italic> Facilitate the Transition between Emetic and Diarrheal Foodborne Pathogens
par: Laura M. Carroll, et autres
Publié: (2020) -
<italic toggle="yes">Bordetella</italic> Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells
par: Jawid Nazir Ahmad, et autres
Publié: (2019) -
Large-Scale Bioinformatics Analysis of <italic toggle="yes">Bacillus</italic> Genomes Uncovers Conserved Roles of Natural Products in Bacterial Physiology
par: Kirk J. Grubbs, et autres
Publié: (2017) -
Global Role of Cyclic AMP Signaling in pH-Dependent Responses in <named-content content-type="genus-species">Candida albicans</named-content>
par: Jeffrey M. Hollomon, et autres
Publié: (2016) -
Effects of liraglutide on lipolysis and the AC3/PKA/HSL pathway
par: Li Z, et autres
Publié: (2019)