Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study

Abstract There are complex potential inter-relationships between the chronic inflammation of asthma and poor control, vitamin D deficiency, musculoskeletal pain and anxiety and depression. The aim was to investigate associations between vitamin D and these possible co-morbidities. This case-controll...

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Autores principales:	Mohammad J. Alkhatatbeh, Haneen S. Almomani, Khalid K. Abdul-Razzak, Shaher Samrah
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Diseases of the respiratory system RC705-779
Acceso en línea:	https://doaj.org/article/2f1b672111634ec894be5d78e42b83e4
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spelling	oai:doaj.org-article:2f1b672111634ec894be5d78e42b83e42021-12-02T16:50:36ZAssociation of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study10.1038/s41533-021-00239-72055-1010https://doaj.org/article/2f1b672111634ec894be5d78e42b83e42021-05-01T00:00:00Zhttps://doi.org/10.1038/s41533-021-00239-7https://doaj.org/toc/2055-1010Abstract There are complex potential inter-relationships between the chronic inflammation of asthma and poor control, vitamin D deficiency, musculoskeletal pain and anxiety and depression. The aim was to investigate associations between vitamin D and these possible co-morbidities. This case-controlled study involved 75 adults with asthma and 75 controls. Serum 25-hydroxyvitamin D (25(OH)D) was measured, levels of anxiety, depression, musculoskeletal pain, and asthma control were assessed. Participants with asthma had lower 25(OH)D and higher anxiety scores and higher measures of musculoskeletal pain compared to controls. Binary logistic regression showed that asthma was associated with decreased 25(OH)D (Odds ratio (OR) = 0.86), general weakness (OR = 13.29), complaint of musculoskeletal pain (OR = 13.73), and increased intensity of musculoskeletal pain (OR = 0.61) and number of painful sites (OR = 2.58). Asthma was not associated with anxiety or depression. Further studies are required to investigate if vitamin D supplementation can improve asthma symptoms and musculoskeletal pain.Mohammad J. AlkhatatbehHaneen S. AlmomaniKhalid K. Abdul-RazzakShaher SamrahNature PortfolioarticleDiseases of the respiratory systemRC705-779ENnpj Primary Care Respiratory Medicine, Vol 31, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the respiratory system RC705-779
spellingShingle	Diseases of the respiratory system RC705-779 Mohammad J. Alkhatatbeh Haneen S. Almomani Khalid K. Abdul-Razzak Shaher Samrah Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study
description	Abstract There are complex potential inter-relationships between the chronic inflammation of asthma and poor control, vitamin D deficiency, musculoskeletal pain and anxiety and depression. The aim was to investigate associations between vitamin D and these possible co-morbidities. This case-controlled study involved 75 adults with asthma and 75 controls. Serum 25-hydroxyvitamin D (25(OH)D) was measured, levels of anxiety, depression, musculoskeletal pain, and asthma control were assessed. Participants with asthma had lower 25(OH)D and higher anxiety scores and higher measures of musculoskeletal pain compared to controls. Binary logistic regression showed that asthma was associated with decreased 25(OH)D (Odds ratio (OR) = 0.86), general weakness (OR = 13.29), complaint of musculoskeletal pain (OR = 13.73), and increased intensity of musculoskeletal pain (OR = 0.61) and number of painful sites (OR = 2.58). Asthma was not associated with anxiety or depression. Further studies are required to investigate if vitamin D supplementation can improve asthma symptoms and musculoskeletal pain.
format	article
author	Mohammad J. Alkhatatbeh Haneen S. Almomani Khalid K. Abdul-Razzak Shaher Samrah
author_facet	Mohammad J. Alkhatatbeh Haneen S. Almomani Khalid K. Abdul-Razzak Shaher Samrah
author_sort	Mohammad J. Alkhatatbeh
title	Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study
title_short	Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study
title_full	Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study
title_fullStr	Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study
title_full_unstemmed	Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study
title_sort	association of asthma with low serum vitamin d and its related musculoskeletal and psychological symptoms in adults: a case-control study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2f1b672111634ec894be5d78e42b83e4
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Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study

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