Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells

Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecules into spatially programmed coacervate-based proto...

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Autores principales: Wiggert J. Altenburg, N. Amy Yewdall, Daan F. M. Vervoort, Marleen H. M. E. van Stevendaal, Alexander F. Mason, Jan C. M. van Hest
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/2f279e085191415dabac0fab918c9cf7
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spelling oai:doaj.org-article:2f279e085191415dabac0fab918c9cf72021-12-02T14:16:32ZProgrammed spatial organization of biomacromolecules into discrete, coacervate-based protocells10.1038/s41467-020-20124-02041-1723https://doaj.org/article/2f279e085191415dabac0fab918c9cf72020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20124-0https://doaj.org/toc/2041-1723Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecules into spatially programmed coacervate-based protocells.Wiggert J. AltenburgN. Amy YewdallDaan F. M. VervoortMarleen H. M. E. van StevendaalAlexander F. MasonJan C. M. van HestNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wiggert J. Altenburg
N. Amy Yewdall
Daan F. M. Vervoort
Marleen H. M. E. van Stevendaal
Alexander F. Mason
Jan C. M. van Hest
Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
description Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecules into spatially programmed coacervate-based protocells.
format article
author Wiggert J. Altenburg
N. Amy Yewdall
Daan F. M. Vervoort
Marleen H. M. E. van Stevendaal
Alexander F. Mason
Jan C. M. van Hest
author_facet Wiggert J. Altenburg
N. Amy Yewdall
Daan F. M. Vervoort
Marleen H. M. E. van Stevendaal
Alexander F. Mason
Jan C. M. van Hest
author_sort Wiggert J. Altenburg
title Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
title_short Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
title_full Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
title_fullStr Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
title_full_unstemmed Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
title_sort programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/2f279e085191415dabac0fab918c9cf7
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