Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells
Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecules into spatially programmed coacervate-based proto...
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Nature Portfolio
2020
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oai:doaj.org-article:2f279e085191415dabac0fab918c9cf72021-12-02T14:16:32ZProgrammed spatial organization of biomacromolecules into discrete, coacervate-based protocells10.1038/s41467-020-20124-02041-1723https://doaj.org/article/2f279e085191415dabac0fab918c9cf72020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20124-0https://doaj.org/toc/2041-1723Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecules into spatially programmed coacervate-based protocells.Wiggert J. AltenburgN. Amy YewdallDaan F. M. VervoortMarleen H. M. E. van StevendaalAlexander F. MasonJan C. M. van HestNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q Wiggert J. Altenburg N. Amy Yewdall Daan F. M. Vervoort Marleen H. M. E. van Stevendaal Alexander F. Mason Jan C. M. van Hest Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells |
description |
Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecules into spatially programmed coacervate-based protocells. |
format |
article |
author |
Wiggert J. Altenburg N. Amy Yewdall Daan F. M. Vervoort Marleen H. M. E. van Stevendaal Alexander F. Mason Jan C. M. van Hest |
author_facet |
Wiggert J. Altenburg N. Amy Yewdall Daan F. M. Vervoort Marleen H. M. E. van Stevendaal Alexander F. Mason Jan C. M. van Hest |
author_sort |
Wiggert J. Altenburg |
title |
Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells |
title_short |
Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells |
title_full |
Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells |
title_fullStr |
Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells |
title_full_unstemmed |
Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells |
title_sort |
programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/2f279e085191415dabac0fab918c9cf7 |
work_keys_str_mv |
AT wiggertjaltenburg programmedspatialorganizationofbiomacromoleculesintodiscretecoacervatebasedprotocells AT namyyewdall programmedspatialorganizationofbiomacromoleculesintodiscretecoacervatebasedprotocells AT daanfmvervoort programmedspatialorganizationofbiomacromoleculesintodiscretecoacervatebasedprotocells AT marleenhmevanstevendaal programmedspatialorganizationofbiomacromoleculesintodiscretecoacervatebasedprotocells AT alexanderfmason programmedspatialorganizationofbiomacromoleculesintodiscretecoacervatebasedprotocells AT jancmvanhest programmedspatialorganizationofbiomacromoleculesintodiscretecoacervatebasedprotocells |
_version_ |
1718391656826273792 |