NLRP3 inflammasome activation results in liver inflammation and fibrosis in mice infected with Schistosoma japonicum in a Syk-dependent manner

Abstract Granulomatous and fibrosing inflammation in response to soluble egg antigen (SEA) from Schistosoma japonicum (S. japonicum) is the main pathological process of S. japonicum infection. Inflammasome activation has recently been implicated in the pathogenesis of liver disease. However, the rol...

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Bibliographic Details
Main Authors: Ya-Qi Lu, Shan Zhong, Nan Meng, Yin-Ping Fan, Wang-Xian Tang
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/2f39ccec01d844b0bdaf2cc11c380d19
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