Skewed distribution of IL-7 receptor-α-expressing effector memory CD8+ T cells with distinct functional characteristics in oral squamous cell carcinoma.

Skewed distribution of IL-7 receptor-α-expressing effector memory CD8+ T cells with distinct functional characteristics in oral squamous cell carcinoma.

CD8(+) T cells play important roles in anti-tumor immunity but distribution profile or functional characteristics of effector memory subsets during tumor progression are unclear. We found that, in oral squamous carcinoma patients, circulating CD8(+) T cell pools skewed toward effector memory subsets...

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Autores principales: Jang-Jaer Lee, Chiou-Yueh Yeh, Chiau-Jing Jung, Ching-Wen Chen, Mao-Kuang Du, Hui-Ming Yu, Chia-Ju Yang, Hui-Yi Lin, Andy Sun, Jenq-Yuh Ko, Shih Jung Cheng, Yen-Liang Chang, Jean-San Chia
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2f3a7dfec095440d8288ab7ddfe942d0
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