Maximizing binary interactome mapping with a minimal number of assays
Comprehensive mapping of binary protein-protein interactions requires to combine several complementary assays. Here, the authors show that complete coverage could be reached with a minimal number of assays as long as they explore various experimental conditions.
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Nature Portfolio
2019
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oai:doaj.org-article:2f419fab78844c44ac0e5edf56d0f33d2021-12-02T14:40:17ZMaximizing binary interactome mapping with a minimal number of assays10.1038/s41467-019-11809-22041-1723https://doaj.org/article/2f419fab78844c44ac0e5edf56d0f33d2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11809-2https://doaj.org/toc/2041-1723Comprehensive mapping of binary protein-protein interactions requires to combine several complementary assays. Here, the authors show that complete coverage could be reached with a minimal number of assays as long as they explore various experimental conditions.Soon Gang ChoiJulien OlivetPatricia CassonnetPierre-Olivier VidalainKatja LuckLuke LambourneKerstin SpirohnIrma LemmensMélanie Dos SantosCaroline DemeretLouis JonesSudharshan RangarajanWenting BianEloi P. CoutantYves L. JaninSylvie van der WerfPhilipp TrepteErich E. WankerJavier De Las RivasJan TavernierJean-Claude TwizereTong HaoDavid E. HillMarc VidalMichael A. CalderwoodYves JacobNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Soon Gang Choi Julien Olivet Patricia Cassonnet Pierre-Olivier Vidalain Katja Luck Luke Lambourne Kerstin Spirohn Irma Lemmens Mélanie Dos Santos Caroline Demeret Louis Jones Sudharshan Rangarajan Wenting Bian Eloi P. Coutant Yves L. Janin Sylvie van der Werf Philipp Trepte Erich E. Wanker Javier De Las Rivas Jan Tavernier Jean-Claude Twizere Tong Hao David E. Hill Marc Vidal Michael A. Calderwood Yves Jacob Maximizing binary interactome mapping with a minimal number of assays |
description |
Comprehensive mapping of binary protein-protein interactions requires to combine several complementary assays. Here, the authors show that complete coverage could be reached with a minimal number of assays as long as they explore various experimental conditions. |
format |
article |
author |
Soon Gang Choi Julien Olivet Patricia Cassonnet Pierre-Olivier Vidalain Katja Luck Luke Lambourne Kerstin Spirohn Irma Lemmens Mélanie Dos Santos Caroline Demeret Louis Jones Sudharshan Rangarajan Wenting Bian Eloi P. Coutant Yves L. Janin Sylvie van der Werf Philipp Trepte Erich E. Wanker Javier De Las Rivas Jan Tavernier Jean-Claude Twizere Tong Hao David E. Hill Marc Vidal Michael A. Calderwood Yves Jacob |
author_facet |
Soon Gang Choi Julien Olivet Patricia Cassonnet Pierre-Olivier Vidalain Katja Luck Luke Lambourne Kerstin Spirohn Irma Lemmens Mélanie Dos Santos Caroline Demeret Louis Jones Sudharshan Rangarajan Wenting Bian Eloi P. Coutant Yves L. Janin Sylvie van der Werf Philipp Trepte Erich E. Wanker Javier De Las Rivas Jan Tavernier Jean-Claude Twizere Tong Hao David E. Hill Marc Vidal Michael A. Calderwood Yves Jacob |
author_sort |
Soon Gang Choi |
title |
Maximizing binary interactome mapping with a minimal number of assays |
title_short |
Maximizing binary interactome mapping with a minimal number of assays |
title_full |
Maximizing binary interactome mapping with a minimal number of assays |
title_fullStr |
Maximizing binary interactome mapping with a minimal number of assays |
title_full_unstemmed |
Maximizing binary interactome mapping with a minimal number of assays |
title_sort |
maximizing binary interactome mapping with a minimal number of assays |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/2f419fab78844c44ac0e5edf56d0f33d |
work_keys_str_mv |
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