Maximizing binary interactome mapping with a minimal number of assays

Comprehensive mapping of binary protein-protein interactions requires to combine several complementary assays. Here, the authors show that complete coverage could be reached with a minimal number of assays as long as they explore various experimental conditions.

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Autores principales: Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre-Olivier Vidalain, Katja Luck, Luke Lambourne, Kerstin Spirohn, Irma Lemmens, Mélanie Dos Santos, Caroline Demeret, Louis Jones, Sudharshan Rangarajan, Wenting Bian, Eloi P. Coutant, Yves L. Janin, Sylvie van der Werf, Philipp Trepte, Erich E. Wanker, Javier De Las Rivas, Jan Tavernier, Jean-Claude Twizere, Tong Hao, David E. Hill, Marc Vidal, Michael A. Calderwood, Yves Jacob
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2f419fab78844c44ac0e5edf56d0f33d
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spelling oai:doaj.org-article:2f419fab78844c44ac0e5edf56d0f33d2021-12-02T14:40:17ZMaximizing binary interactome mapping with a minimal number of assays10.1038/s41467-019-11809-22041-1723https://doaj.org/article/2f419fab78844c44ac0e5edf56d0f33d2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11809-2https://doaj.org/toc/2041-1723Comprehensive mapping of binary protein-protein interactions requires to combine several complementary assays. Here, the authors show that complete coverage could be reached with a minimal number of assays as long as they explore various experimental conditions.Soon Gang ChoiJulien OlivetPatricia CassonnetPierre-Olivier VidalainKatja LuckLuke LambourneKerstin SpirohnIrma LemmensMélanie Dos SantosCaroline DemeretLouis JonesSudharshan RangarajanWenting BianEloi P. CoutantYves L. JaninSylvie van der WerfPhilipp TrepteErich E. WankerJavier De Las RivasJan TavernierJean-Claude TwizereTong HaoDavid E. HillMarc VidalMichael A. CalderwoodYves JacobNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Soon Gang Choi
Julien Olivet
Patricia Cassonnet
Pierre-Olivier Vidalain
Katja Luck
Luke Lambourne
Kerstin Spirohn
Irma Lemmens
Mélanie Dos Santos
Caroline Demeret
Louis Jones
Sudharshan Rangarajan
Wenting Bian
Eloi P. Coutant
Yves L. Janin
Sylvie van der Werf
Philipp Trepte
Erich E. Wanker
Javier De Las Rivas
Jan Tavernier
Jean-Claude Twizere
Tong Hao
David E. Hill
Marc Vidal
Michael A. Calderwood
Yves Jacob
Maximizing binary interactome mapping with a minimal number of assays
description Comprehensive mapping of binary protein-protein interactions requires to combine several complementary assays. Here, the authors show that complete coverage could be reached with a minimal number of assays as long as they explore various experimental conditions.
format article
author Soon Gang Choi
Julien Olivet
Patricia Cassonnet
Pierre-Olivier Vidalain
Katja Luck
Luke Lambourne
Kerstin Spirohn
Irma Lemmens
Mélanie Dos Santos
Caroline Demeret
Louis Jones
Sudharshan Rangarajan
Wenting Bian
Eloi P. Coutant
Yves L. Janin
Sylvie van der Werf
Philipp Trepte
Erich E. Wanker
Javier De Las Rivas
Jan Tavernier
Jean-Claude Twizere
Tong Hao
David E. Hill
Marc Vidal
Michael A. Calderwood
Yves Jacob
author_facet Soon Gang Choi
Julien Olivet
Patricia Cassonnet
Pierre-Olivier Vidalain
Katja Luck
Luke Lambourne
Kerstin Spirohn
Irma Lemmens
Mélanie Dos Santos
Caroline Demeret
Louis Jones
Sudharshan Rangarajan
Wenting Bian
Eloi P. Coutant
Yves L. Janin
Sylvie van der Werf
Philipp Trepte
Erich E. Wanker
Javier De Las Rivas
Jan Tavernier
Jean-Claude Twizere
Tong Hao
David E. Hill
Marc Vidal
Michael A. Calderwood
Yves Jacob
author_sort Soon Gang Choi
title Maximizing binary interactome mapping with a minimal number of assays
title_short Maximizing binary interactome mapping with a minimal number of assays
title_full Maximizing binary interactome mapping with a minimal number of assays
title_fullStr Maximizing binary interactome mapping with a minimal number of assays
title_full_unstemmed Maximizing binary interactome mapping with a minimal number of assays
title_sort maximizing binary interactome mapping with a minimal number of assays
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/2f419fab78844c44ac0e5edf56d0f33d
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