Infectious endotheliitis: a rare case of presumed mycotic origin

Luis Fernando Zapata,1 José David Paulo,1 Carlos A Restrepo,1 Luis Fernando Velásquez,2 Andrés E Toro Montoya,2 Melissa A Zapata21Department of Ophthalmology Hospital Pablo Tobón Uribe; 2School of Medicine, Universidad Pontificia Bolivariana, Medell&ia...

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Autores principales:	Zapata LF, Paulo JD, Restrepo CA, Vel&aacute;squez LF, Toro Montoya&nbsp;AE, Zapata MA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/2f49dde375f7433e95382240327bccf8
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spelling	oai:doaj.org-article:2f49dde375f7433e95382240327bccf82021-12-02T02:13:49ZInfectious endotheliitis: a rare case of presumed mycotic origin1177-54671177-5483https://doaj.org/article/2f49dde375f7433e95382240327bccf82013-07-01T00:00:00Zhttp://www.dovepress.com/infectious-endotheliitis-a-rare-case-of-presumed-mycotic-origin-a13697https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Luis Fernando Zapata,1 José David Paulo,1 Carlos A Restrepo,1 Luis Fernando Velásquez,2 Andrés E Toro Montoya,2 Melissa A Zapata21Department of Ophthalmology Hospital Pablo Tobón Uribe; 2School of Medicine, Universidad Pontificia Bolivariana, Medellín, ColombiaPurpose: To report an interesting case of infectious endotheliitis of presumed mycotic origin.Methods: A case report of a 56-year-old male farmer who sought medical attention after a month-long evolution of irritative symptoms in his right eye, accompanied by visual acuity (VA) impairment. The patient received topical and oral broad-spectrum antibiotic treatment with no improvement before being referred to a cornea specialist, where he was found to have VA of 20/150 and was noted on biomicroscopy to have endothelial feathery coalescent lesions. The patient was admitted to the hospital for an aqueous humor sample and intravenous voriconazole.Results: The microbiological studies did not isolate any micro-organisms. However, clinical evidence of improvement was confirmed after 5 days of antimycotic intravenous therapy. Complete clinical resolution was achieved at 1 month after treatment completion with oral voriconazole, as evidenced by VA of 20/20 and disappearance of endothelial lesions.Conclusion: Endothelial involvement by fungi is a rare condition. In this case, no microbes were isolated, but the characteristic morphology of the lesions, the history of onychomycosis, and the spectacular response to voriconazole turn this case into a valid presumptive diagnosis.Keywords: endotheliitis, mycotic, keratitis, voriconazoleZapata LFPaulo JDRestrepo CAVel&aacute;squez LFToro Montoya&nbsp;AEZapata MADove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1459-1461 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Zapata LF Paulo JD Restrepo CA Vel&aacute;squez LF Toro Montoya&nbsp;AE Zapata MA Infectious endotheliitis: a rare case of presumed mycotic origin
description	Luis Fernando Zapata,1 José David Paulo,1 Carlos A Restrepo,1 Luis Fernando Velásquez,2 Andrés E Toro Montoya,2 Melissa A Zapata21Department of Ophthalmology Hospital Pablo Tobón Uribe; 2School of Medicine, Universidad Pontificia Bolivariana, Medellín, ColombiaPurpose: To report an interesting case of infectious endotheliitis of presumed mycotic origin.Methods: A case report of a 56-year-old male farmer who sought medical attention after a month-long evolution of irritative symptoms in his right eye, accompanied by visual acuity (VA) impairment. The patient received topical and oral broad-spectrum antibiotic treatment with no improvement before being referred to a cornea specialist, where he was found to have VA of 20/150 and was noted on biomicroscopy to have endothelial feathery coalescent lesions. The patient was admitted to the hospital for an aqueous humor sample and intravenous voriconazole.Results: The microbiological studies did not isolate any micro-organisms. However, clinical evidence of improvement was confirmed after 5 days of antimycotic intravenous therapy. Complete clinical resolution was achieved at 1 month after treatment completion with oral voriconazole, as evidenced by VA of 20/20 and disappearance of endothelial lesions.Conclusion: Endothelial involvement by fungi is a rare condition. In this case, no microbes were isolated, but the characteristic morphology of the lesions, the history of onychomycosis, and the spectacular response to voriconazole turn this case into a valid presumptive diagnosis.Keywords: endotheliitis, mycotic, keratitis, voriconazole
format	article
author	Zapata LF Paulo JD Restrepo CA Vel&aacute;squez LF Toro Montoya&nbsp;AE Zapata MA
author_facet	Zapata LF Paulo JD Restrepo CA Vel&aacute;squez LF Toro Montoya&nbsp;AE Zapata MA
author_sort	Zapata LF
title	Infectious endotheliitis: a rare case of presumed mycotic origin
title_short	Infectious endotheliitis: a rare case of presumed mycotic origin
title_full	Infectious endotheliitis: a rare case of presumed mycotic origin
title_fullStr	Infectious endotheliitis: a rare case of presumed mycotic origin
title_full_unstemmed	Infectious endotheliitis: a rare case of presumed mycotic origin
title_sort	infectious endotheliitis: a rare case of presumed mycotic origin
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/2f49dde375f7433e95382240327bccf8
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Infectious endotheliitis: a rare case of presumed mycotic origin

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